The Skin Microbiome in Graft Versus Host Disease

Last updated: March 31, 2025
Sponsor: University Hospital, Basel, Switzerland
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

N/A

Treatment

additional blood sampling

Skin punch biopsies

Skin swabs

Clinical Study ID

NCT04231500
2019-01939; sp19Mueller5
  • Ages > 18
  • All Genders

Study Summary

Based on the evidence on the impact of the intestinal microbiome on the Graft Versus Host Disease (GVHD) after allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT), it is hypothesized that the skin-microbiome may play a role in cutaneous GVHD as well. Therefore, this study aims at investigating the skin-microbiota of patients with GVHD after allo-HSCT and of patients without GVHD after allo-HSCT.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • undergoing allo-HSCT at the University Hospital Basel

Exclusion

Exclusion Criteria:

  • missing ability to judge

  • illiteracy or lack of German, French or English language

Study Design

Total Participants: 74
Treatment Group(s): 3
Primary Treatment: additional blood sampling
Phase:
Study Start date:
March 01, 2023
Estimated Completion Date:
March 31, 2026

Connect with a study center

  • Department of Dermatology; University Hospital Basel

    Basel, 4031
    Switzerland

    Site Not Available

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