IMPact on Revascularization Outcomes of IVUS Guided Treatment of Complex Lesions and Economic Impact

Inclusion Criteria:

• Age ≥ 18 years at screening

• PCI with stent implantation involving a high risk or complex lesion defined asinvolving at least one of the following characteristics:

• Chronic total occlusion

• In-stent restenosis

• Severe coronary artery calcification

• Long lesion (≥ 28 mm in length)

• Bifurcation lesion (Any Medina class that involves main branch disease with a sidebranch ≥2.0 mm)

• Stable angina, unstable angina, or non-ST Elevation myocardial infarction (NSTEMI),undergoing PCI of a single or multivessel coronary artery stenosis

• PCI performed with either angiography alone, or IVUS guidance used

Exclusion Criteria:

• Subjects with acute ST elevation myocardial infarction (STEMI), or cardiogenic shock

• Use of fibrinolytic therapy within 24 hours of PCI

• Planned revascularization of a target vessel as a staged procedure

• Stent thrombosis

• Use of optical coherence tomography (OCT) during the index procedure