Effect of Acupuncture on Patients With Crohn's Disease in Remission

Inclusion Criteria:

1. aged 16-70;

2. patients in remission (CDAI < 150);

3. patients were not taking medication or were only taking one or more of the followingdrugs: [prednisone ≤15mg/d, azathioprine (≤1mg/kg/d), methotrexate (≤15mg/w) ormesalazine (≤4g/d)] and prednisone was used for at least 1 month, whileazathioprine, methotrexate or mesalazine was used for at least 3 months;

4. those who did not use TNF alpha and other preparations within 3 months beforeentering the study;

5. those who have never experienced acupuncture;

6. patients signing informed consent.

Exclusion Criteria:

1. patients who are recently pregnant or in pregnancy or lactation;

2. patients with serious organic diseases;

3. patients diagnosed as psychosis;

4. patients who take antibiotics, probiotics, traditional Chinese medicine and otherdrugs at the same time, or who suffer from multiple diseases and need to take otherdrugs for a long time, and may affect the observation of the efficacy of this trial;

5. severe skin diseases (such as erythema nodosum, pyoderma gangrenosum, etc.), eyediseases (such as iritis, uveitis, etc.), thromboembolic diseases and other seriousextraintestinal manifestations;

6. there are serious intestinal fistula, abdominal abscess, intestinal stenosis andobstruction, perianal abscess, gastrointestinal hemorrhage, intestinal perforationand other complications;

7. patients with short bowel syndrome who have undergone abdominal or gastrointestinalsurgery in the past half a year;

8. there are skin diseases or defects in the selected area of acupuncture andmoxibustion that cannot be performed.