Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing BMT

Phase

N/A

Condition

Blood Cancer

Cancer/tumors

Hematologic Neoplasms

Treatment

Medication Review

Patient satisfaction questionnaire

Nutrition assessment

Clinical Study ID

NCT04194840

CASE9Z19

All Genders

Study Summary

As the average age of individuals undergoing stem cell transplant continues to increase, challenges associated with balancing the side effects of cancer treatments while also managing other medical conditions develop. Studies have shown these individuals develop more treatment related side effects and take longer to leave the hospital due to complications. The purpose of this study is to develop a multiple provider clinic that will help identify any additional needs in the more complicated and generally older transplant patient population. If needed, this clinic will recommend interventions or referrals to the appropriate specialties to the participant and the transplant physician for the participant before your transplant procedure. Examples of potential areas of improvement include a course of physical therapy, nutritional supplements, or modifications of medications, among others with the goal to make your transplant safer and to decrease length of time in the hospital.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Deemed candidate for autologous or allogeneic transplantation by their Stem CellTransplant Attending Physician
Stem cell transplant candidates > 60 years
Younger patients with age adjusted HCT- CMI> 4
Outpatient at time of enrollment.
Must have at a minimum 4 weeks and a maximum of 12 weeks before anticipated start oftransplant procedures, ie initiation of preparation regimen or beginning ofperipheral stem cell mobilization
Must have transportation to outpatient appointments
Must be able to read and understand English to complete the required questionnairesMust be able to read and understand protocol consent

Exclusion

Exclusion Criteria:

Those who are not felt to be candidates for autologous or allogeneic stem celltransplantation

Study Design

Medication Review

May 01, 2021

March 28, 2025

Study Description

This is a supportive interventional study to assess frailty in at risk geriatric cancer patients undergoing stem cell transplant and to determine if specific interventions are feasible and will improve overall outcomes.

A total of 20 participants will be enrolled in this study with the first 10 participants limited to myeloma or lymphoma patients who meet eligibility criteria and are candidates for autologous transplantation. The second 10 participants enrolled will be either allogeneic or autologous stem cell transplant candidates who meet eligibility criteria.

The objectives of this study are as follows:

To pilot a comprehensive multidisciplinary geriatric assessment clinic.
To determine whether a comprehensive geriatric assessment (outside of physical therapy assessment) can be performed in a time efficient manner. The goal is to complete all questionnaires and the multidisciplinary assessments in <90 minutes.
To assess participant and physician satisfaction
To determine if interventions recommended in the clinic are achievable for each participant
Examples of interventions could include, medication changes, management of depression, dietary modifications, physical therapy three times a week, etc.
To determine if participation in the transplant wellness clinic reduces length of stay and readmission rate compared to historical controls at our institution

Connect with a study center

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
Cleveland, Ohio 44106
United States
Site Not Available

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.