Relationship-Based Intervention for Post-Partum Depression

Last updated: May 27, 2024
Sponsor: Interdisciplinary Center Herzliya
Overall Status: Active - Recruiting

Phase

N/A

Condition

Depression

Treatment

Post-partum depression- Dyadic psychotherapy-

Post-partum depression- Psycho-educational therapy

Clinical Study ID

NCT04193462
InterdisciplinaryCH
  • Female
  • Accepts Healthy Volunteers

Study Summary

A short term dyadic psychotherapy intervention for mothers with Post-Partum depression and their babies in the first year of life was developed. The investigators believe that following dyadic intervention mothers will show improvement in depressive symptoms, the quality of the mother-child relationship will improve, and maternal and infant's oxytocin levels will rise.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • women diagnosed with Post-Partum depression, major or minor, according to theDiagnostic and Statistical Manual of Mental Disorders, 5th version (DSM-5)

  • 3-8 months after birth of one baby

Exclusion

Exclusion Criteria:

  • Mothers of twins

  • Mothers of premature babies

  • Comorbidity of psychopathology, women who have severe personality disorder or otherpsychiatric diagnose, besides depression or anxiety

  • Women or babies who suffer from severe medical condition, such as developmentalproblems for the baby or disability.

Study Design

Total Participants: 100
Treatment Group(s): 2
Primary Treatment: Post-partum depression- Dyadic psychotherapy-
Phase:
Study Start date:
May 08, 2019
Estimated Completion Date:
December 31, 2024

Study Description

Subjects: 60 Mothers will be interviewed and diagnosed as suffering from Post-Partum- depression (PPD) according to the Diagnostic and Statistical Manual of Mental Disorders, IV version (DSM-IV), enrolling within 3-8 months postpartum. Mothers will be recruited through social media networks. Additional 40 mothers, 3-8 months postpartum will be assessed and diagnosed as not suffering from PPD or any other psychiatric psychopathology.

Procedure: The baseline assessment will be conducted at the infant's home. A parent-infant interaction will be videotaped and salivary oxytocin samples will be collected from the infant and from the mother.

The women in the PPD group will participate in 8 weeks of dyadic psychotherapy (DP) combining video feedback, or a psycho-educational treatment regarding child development (randomize selection will be made). During the 8-week treatment, salivary oxytocin samples will be collected from the infants and from the mother at the beginning and the end of each session.

Another assessment will be conducted at the infant's home, at the end of the treatment. As in the baseline condition, this assessment will include videotaped parent-infant interaction, as well as salivary oxytocin samples collection from the mother and from the infant. Parent-infant interaction will be filmed and assessed using the CIB Manual (Feldman, 1998) and the synchrony coding system.

Healthy mothers will undergo the same baseline assessment and a second assessment within 2-3 months, and won't get any treatment.

Connect with a study center

  • Interdisciplinary Center

    Herzliya, 4610101
    Israel

    Active - Recruiting

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