Comparative Effectiveness of Direct Admission & Admission Through Emergency Departments for Children

Last updated: August 1, 2024
Sponsor: Dartmouth-Hitchcock Medical Center
Overall Status: Completed

Phase

N/A

Condition

Pediatric Health

Treatment

ED admission

Direct admission

Clinical Study ID

NCT04192799
IHS-2018C2-12902-IC
  • Ages 30-17
  • All Genders

Study Summary

At a national level, emergency departments (EDs) serve as the portal of hospital admission for 75% of hospitalized children. The remainder occur via direct admission, defined as admission to hospital without first receiving care in the hospital's ED. The overall goals of this research are to: (i) implement pediatric direct admission systems at 3 hospitals, (ii) compare the timeliness of healthcare delivery for children who are admitted directly and through emergency departments, (iii) determine which patient populations achieve the greatest benefits from direct admission, and (iv) identify barriers and facilitators of successful implementation.

Eligibility Criteria

Inclusion

Inclusion Criteria

Child has one of the following presenting diagnoses:

  • gastroenteritis

  • dehydration

  • skin and soft tissue infection

  • urinary tract infection/pyelonephritis

  • pneumonia

  • viral infection not otherwise specified

  • influenza

Exclusion Criteria

Ineligible children include those:

  • with planned admissions (i.e., chemotherapy)

  • admitted to non-pediatric hospital medicine services (i.e., intensive care)

  • transferred from other hospitals

Study Design

Total Participants: 1997
Treatment Group(s): 2
Primary Treatment: ED admission
Phase:
Study Start date:
February 01, 2020
Estimated Completion Date:
July 31, 2023

Study Description

The Specific Aims of this research are to: (i) Determine the effect of a pediatric direct admission system on timeliness of healthcare provision (the investigator's primary outcome), family experience of care, and rates of clinical deterioration compared to hospital admission beginning in the ED; (ii) Identify the pediatric populations and conditions that experience the greatest benefits from direct admission; and (iii) Through interviews with key informants, identify barriers to and facilitators of implementing standardized direct admission processes.

To achieve these Aims, a stepped-wedge cluster randomized controlled trial at three geographically diverse hospitals in the United States will be conducted, randomizing primary and urgent care practices in the hospitals' catchment area to cross over to the direct admission intervention at four time points. Linear models with random effects for clusters and time period fixed effects will be used to evaluate outcomes associated with the direct admission intervention. To examine for heterogeneity of treatment effects, interactions between direct admission and a priori-specified subgroups will be examined.

Connect with a study center

  • Nationwide Children's Hospital

    Columbus, Ohio 43205
    United States

    Site Not Available

  • UPMC Children's Hospital of Pittsburgh

    Pittsburgh, Pennsylvania 15224
    United States

    Site Not Available

  • Providence Regional Medical Center - Everett

    Everett, Washington 98201
    United States

    Site Not Available

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