New Technologies for Intensive Prevention Programs - NET-IPP

Last updated: October 2, 2024
Sponsor: Herzzentrum Bremen
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Atherosclerosis

Coronary Artery Disease

Chest Pain

Treatment

Web-based prevention program

Clinical Study ID

NCT04143646
BIHKF 3
  • Ages > 18
  • All Genders

Study Summary

In a randomized trial patients hospitalized for myocardial infarction are prospectively enrolled and assigned to either a web-based intensive prevention program or usual care (1 : 1 randomization). The web-based program includes telemetric transmission of data on cardiocascular risk factors (physical activity, blood pressure, body weight) by patients to the study center, e-learning modules by the study center and repetitive electronic contacts by e-mails and apps between a prevention assistant and the patient.

In addition, genetic risk on cardiovascular events will be assessed in all patients of the intervention group by a polygenetic risk score (PRS). Patients of the intervention group are randomly assigned to disclosure of genetic risk vs. no disclosure. The study hypothesis is that disclosure of genetic risk improves cardiovascular risk factor control by increased patient motivation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Hospitalization due to acute myocardial infarction (ST-elevation or non-ST-elevationmyocardial infarction) defined according to valid international guidelines

  2. Access to internet and consent to participate in a web-based prevention program

  3. Consent for genetic risk assessment for cardiovascular events and risk disclosureaccording to randomization

Exclusion

Exclusion Criteria:

  1. Patient refusal or inability to give informed consent

  2. Hemodynamically significant valvular heart disease

  3. Exercise limitations due to clinical conditions not related to CAD (such as severeorthopedic disorders,..)

  4. Any major non-cardiac condition that would adversely affect survival during theduration of the study (such as cancer with prognosis < 2 years,..)

  5. Inability to cooperate with the protocol, including longterm follow-up

  6. Chronic drug and alcohol abuse

Study Design

Total Participants: 864
Treatment Group(s): 1
Primary Treatment: Web-based prevention program
Phase:
Study Start date:
May 01, 2020
Estimated Completion Date:
June 30, 2026

Connect with a study center

  • Herzzentrum Bremen

    Bremen, 28277
    Germany

    Site Not Available

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