A Trial of Total Versus Partial Omentectomy for Advanced Gastric Cancer in Gastrectomy

Inclusion Criteria:

1. Had been treated with Radical resection (D2, R0) of gastric cancer (Lymph node≥16);

2. Physical condition and organ function allows to tolerable abdominal surgery;

3. Willing and able to comply with the program during the study period;

4. Written informed consent provided;

5. ≥ 18 and ≤ 70 years of age; preoperative gastric cancer patients with pathologicallyconfirmed;

6. With more than a 6-month life expectancy;

7. No other serious concomitant diseases; Sufficient organ functions;

8. No previous history of chemotherapy or radiotherapy;

9. All patients accept 8 cycles XELOX chemotherapy regimen;

10. Clinical stage: T2-4aN0-+M0;

11. Macroscopic types :Borrmann I-III;

12. Not greater curvature tumor;

13. No previous surgery for any abdominal disease, except an appendectomy forappendicitis, a laparoscopic cholecystectomy for gallbladder stones; No previoushistory of peritonitis, pancreatitis;

14. Karnofsky performance status (KPS)>60; Eastern Cooperative Oncology Group PerformanceStatus (ECOG): 0-1.

Exclusion Criteria:

1. Pregnancy or breast feeding;

2. Patients with Serious liver disease (such as cirrhosis, etc.), kidney disease,respiratory disease or uncontrolled diabetes, hypertension and other chronic systemicdiseases, heart disease with Clinical symptoms, such as congestive heart failure,coronary heart disease symptoms, drug is difficult to control arrhythmia,hypertension, or six months had a myocardial infarction attack, or cardiacinsufficiency;

3. Organ transplantation patients need immunosuppressive therapy;

4. Severe recurrent infections were not controlled or with other serious concomitantdiseases;

5. Patients got other primary malignant tumors (except curable skin basal cell carcinomaand cervical cancer in situ) except gastric cancer within 5 years;

6. Psychiatric disease which require treatment;

7. Have the history of organ transplantation;

8. Within 6 months before study starts and in the process of this study, patientsparticipate in other clinical researches.

9. Advanced gastric cancer with omentum invasion

10. Patients can't treated with XELOX after surgery;

11. Macroscopic types : Borrmann IV;

12. Tumor invasion of adjacent organ (T4b) or with distant metastasis（M1）;

13. Tumor invasion the greater curvature invasion.