TRAIN-BW: Backward Walking Training in Multiple Sclerosis

Last updated: December 11, 2023
Sponsor: Wayne State University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Multiple Sclerosis

Memory Loss

Neurologic Disorders

Treatment

Forward Walking Training

Backward Walking Training

Clinical Study ID

NCT04091464
URG20192020
  • Ages > 18
  • All Genders

Study Summary

Individuals with multiple sclerosis (MS) experience in impairments in mobility and cognition that increase the risk for accidental falls. More than 50% of individuals with MS experience injurious falls within a 6-month period. Current interventions to improve fall risk have focused on forward walking (FW) and balance training, resulting in small declines in the relative risk for falls with a large degree of variability. Interestingly, motor differences between MS and healthy controls are more pronounced in backward walking (BW), yet no studies have investigated BW training as an intervention to reduce fall risk in persons with MS. This study will investigate the feasibility, acceptability and impact of BW training compared to forward walking training on motor function and fall risk in persons with MS.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Diagnosis of MS
  • PDDS <6, indicating ability to ambulate with or without an assistive device >/= 50% ofthe time
  • Self-reported walking dysfunction as evidenced by a score of >/= 30 on MSWS-12 ORreports of 2 or more falls in the prior 6 months, indicating a frequent faller.

Exclusion

Exclusion Criteria:

  • MS relapse within the past 30 days
  • comorbid neurological disorder
  • acute orthopedic disorder/injury
  • unable to follow study-related commands

Study Design

Total Participants: 90
Treatment Group(s): 2
Primary Treatment: Forward Walking Training
Phase:
Study Start date:
January 01, 2020
Estimated Completion Date:
June 30, 2025

Connect with a study center

  • Wayne State University

    Detroit, Michigan 48201
    United States

    Active - Recruiting

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