Phase
Condition
N/ATreatment
Custom Thoracolumbosacral Orthosis
Placebos
AbobotulinumtoxinA
Clinical Study ID
Ages 10-16 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion criteria:
Clinically determined idiopathic nature of scoliosis
Age 10-16 years
Risser stage 0,1,or 2
major curve of 20°-40°
curve apex caudal to T7 vertebra
ability to adhere to bracing protocol
Botulinum toxin naïve or previously treated greater than 6 months prior to studyentry
Exclusion
Exclusion criteria:
Diagnosis of congenital scoliosis, neuromuscular scoliosis, or other "reason" forscoliosis - Previous surgery at any segment of the spine
Current need for surgery at any level of the spine
Treatment with any drug known to interfere with neuromuscular function
Any other medical condition, laboratory or diagnostic procedure finding that mightpreclude administration of BTX
Ongoing infection at the injection sites
Diagnosis as either resistant or sensitive to botulinum toxin treatment of any typeor to any components of the BTX formulation
Cow milk protein allergy
Study Design
Study Description
Connect with a study center
Johns Hopkins University
Baltimore, Maryland 21287
United StatesActive - Recruiting
Not the study for you?
Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.