The Effect of Intermittent Theta Burst Stimulation (iTBS) in Patients With Alcohol Use Disorder

Last updated: March 23, 2020
Sponsor: Shanghai Mental Health Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Alcohol Use Disorder

Substance Abuse

Alcohol Dependence

Treatment

N/A

Clinical Study ID

NCT03932149
JDu-007
  • Ages 18-65
  • All Genders

Study Summary

The aim of this trial is to investigate the efficacy of left DLPFC iTBS in a population of alcohol use disorder patients, compared with the sham iTBS. Moreover, this trial will conduct follow-up assessments to evaluate whether its efficacy can sustain for a long time if it is effective.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • a DSM-5 diagnosis of alcohol use disorder

  • age between 18 and 65

  • can return to the research center for successive visits.

Exclusion

Exclusion Criteria:

  • severe cognitive impairment

  • current DSM-5 diagnosis of schizophrenia or another psychotic disorder

  • current other substance abuse (except nicotine)

  • severe organic diseases

  • rTMS contraindications (such as a history of epileptic seizures, metal implants nearthe head).

Study Design

Total Participants: 60
Study Start date:
December 06, 2019
Estimated Completion Date:
March 31, 2021

Study Description

Alcohol abuse and alcohol use disorder are important major health issues in our modern society. However, the treatment of alcohol addiction is currently limited to the treatment of acute withdrawal symptoms, but lacks effective interventions to reduce craving and prevent relapse. In an attempt to improve the treatment of substance dependence, non-invasive neuromodulation has gained attention as a new potential treatment option. The aim of this trial is to investigate the efficacy of left DLPFC iTBS in a population of alcohol use disorder patients, compared with the sham iTBS. Moreover, this trial will conduct follow-up assessments to evaluate whether its efficacy can sustain for a long time if it is effective.

Connect with a study center

  • Shanghai Mental Health Center

    Shanghai, Shanghai 200000
    China

    Active - Recruiting

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