Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure

Last updated: February 25, 2025
Sponsor: Universitaire Ziekenhuizen KU Leuven
Overall Status: Active - Recruiting

Phase

N/A

Condition

Recurrent Pregnancy Loss

Treatment

Control

PGT-A

Clinical Study ID

NCT03900780
S62302
  • Ages 18-40
  • Female

Study Summary

Assessing whether Preimplantation Genetic Testing for Aneuploidy (PGT-A) can increase the ongoing pregnancy rate per transferred embryo and can decrease the time to pregnancy and miscarriage rate in patients with Recurrent Implantation Failure (RIF)

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Women with recurrent implantation failure (previous transfer of least 4 good qualityembryos in at least 3 fresh or frozen cycles)

  • BMI < 35

  • Normal hysteroscopy

Exclusion

Exclusion Criteria:

  • thin endometrium in previous cycles (<6mm), endometriosis ASRM score III-IV,premature ovarian failure (POF, Bologna criteria), abnormal karyotype, donor oocytesor embryos, PGT-M

Study Design

Total Participants: 100
Treatment Group(s): 2
Primary Treatment: Control
Phase:
Study Start date:
May 01, 2019
Estimated Completion Date:
December 31, 2026

Connect with a study center

  • UZ Leuven

    Leuven, 3000
    Belgium

    Active - Recruiting

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