Phase
Condition
Thrombosis
Blood Clots
Occlusions
Treatment
N/AClinical Study ID
Ages 14-85 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Han population with age greater than or equal to 14 years old and less than or equalto 85 years;
Signed informed consent;
confirmed initial acute pulmonary embolism, within 2 weeks of disease, pulmonaryembolism confirmed methods include: CTA/DSA/pulmonary ventilation Imaging: confirmedas at least 1 trunk pulmonary artery or proximal low lobe artery filling defect;
risk stratification for intermediate high-risk or high-risk pulmonary embolism: 2014ESC stratified definition of high-risk and high-risk: high-risk PE: hemodynamicsObstruction, systolic blood pressure <90mmHg, greater than 15 minutes; medium and highrisk PE: right ventricular dysfunction imaging findings (RV / LV ≥ 0.9) and myocardialdamage indicators positive (TNT > 0.1 ng / ml);
blood flow at admission The kinetics are stable.
Exclusion
Exclusion Criteria:
patients with mental illness can not cooperate with the completion of the study; -CTPA / DSA contraindications patients;
any contraindications listed in the instructions for treatment of the drug involved inthe study;
diseases associated with coagulopathy leading to the risk of clinically relevantbleeding;
There are active bleeding or high risk of bleeding in patients with anticoagulantthrombolysis contraindications;
creatinine clearance rate <30 mL / min;
life expectancy ≤ 6 months;
childbearing age or pregnancy, lactation period without appropriate contraceptivemeasures Subjects;
participated in any other drug or medical device study within 30 days prior torandomization;
cases that the investigator considered unsuitable for participation in the trial.
Study Design
Connect with a study center
The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi 710061
ChinaActive - Recruiting
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