DIMES - DIgital MEdicine Study for Adults With Schizophrenia, Bipolar I Disorder, or Major Depression Currently Using Aripiprazole

Inclusion Criteria:

• Patients aged 18 years of age or older.

• Patients with a primary diagnosis of schizophrenia (including schizoaffectivedisorder), bipolar I disorder, or major depressive disorder based on the DiagnosticStatistical Manual of Mental Disorders, 5th edition (DSM-5) criteria.

• Patients have an active prescription for oral Aripiprazole.

• Patients may have general medical conditions that are deemed safe for the patient toenter an interventional trial per investigator judgment.

• Patients deemed fit for participation in the study by verbal or written confirmationfrom their mental health provider

Exclusion Criteria:

• Patients with a current neurocognitive disorder (i.e. dementia), intellectualdisorder, or any other diagnosis that could impact the patient's ability toparticipate in the trial.

• Any patient who, in the opinion of the patient's mental health provider, studyphysician or investigator, is unfit to participate in the trial.

• Any patient who has participated in an investigational drug trial 30 days prior totrial enrollment.

• Females who are breastfeeding, and/or who have a positive pregnancy test prior totrial enrollment, or females who are planning to become pregnant during the trial. Noclinical trials have been conducted on the use of ABILIFY MYCITE during pregnancy orbreastfeeding.

• Patients who do not have skin on the anterior chest just above the lower edge of therib cage that is free of any dermatological problems (e.g., dermatosis or dermatitis,open wounds, or other skin disorders such as warts, rashes, atopic dermatitis, orirritations).

• Patients who are unwilling to refrain from the use of topical products on the skinpatch sites.

• Has 2 or more errors on the brief, 6-item cognitive screener administered at baseline.

• <20% Proportion of Days Covered (PDC) Aripiprazole over the last 6 months prior toenrollment. This is to ensure that all individuals enrolled will have at least filledtheir Aripiprazole prescription.