The Effect of Experimental Neck Pain in Healthy Participants

Last updated: February 19, 2019
Sponsor: Aalborg University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neck Pain

Chronic Pain

Treatment

N/A

Clinical Study ID

NCT03848247
N-20180063_Sub-project_1
  • Ages 18-50
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study investigates if/how an experimentally applied muscle pain/soreness, lasting for some days may affect brain activity, balance, movement patterns, muscle function and pain sensitivity in a healthy population

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Healthy men and women aged 18-50 years

  • Only for sub-projects 1 and 2: Right-handed

  • Able to speak, read and understand Danish and English

Exclusion

Exclusion Criteria:

  • Pain from the neck or shoulder area during the past 6 months

  • Experience of delayed onset muscle soreness (DOMS) during the week leading up to thetest session

  • Former surgery in neck or shoulder

  • Current or previous chronic or recurrent pain condition

  • Pregnancy

  • Drug addiction defined as the use of cannabis, opioids or other drugs

  • Previous neurologic, musculoskeletal or mental illnesses

  • Regular use of analgesics

  • Abnormally disrupted sleep in the last 24 hours preceding the experiment

  • Lack of ability to cooperate

  • Unable to pass the TASS safety screening questionnaire for TMS

Study Design

Total Participants: 40
Study Start date:
January 21, 2019
Estimated Completion Date:
May 01, 2019

Study Description

All included healthy volunteers will participate in test-sessions on 4 separate days over approximately 2 weeks.

During the study participants will be randomised into and either a control group (injection of isotonic saline into a neck muscle) or neck pain group (injection of Nerve Growth Factor (NGF) into a neck muscle).

Alle participants tested with regards to:

Brain activity related to neck muscles will be estimated using TMS Balance will be tested using a force place Body movements will be recorded using 3D tracking Muscle activity will be estimated using electromyography (EMG)

Connect with a study center

  • Dept. Of Health Science and Technology, SMI, Aalborg University

    Aalborg, 9220
    Denmark

    Active - Recruiting

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