Application of Virtual Mandibular Position in Temporomandibular Jont Reconstruction With Costochondral Graft in Children Jaw Deformity

Last updated: April 7, 2023
Sponsor: Peking University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Birth Defects

Holoprosencephaly

Treatment

N/A

Clinical Study ID

NCT03845088
schen
  • Ages 6-12
  • All Genders

Study Summary

Hypothesis:Computer-aided design virtual mandibular position is feasible for costochondral graft growing and occlusion stabilizing in the one-stage treatment of children temporomandibular joint ankylosis (TMJA) or condyle absence with jaw deformity.

Methods: The inclusion criteria is children patients younger than 12 years old with unilateral TMJA or condyle absence. A virtual mandibular position is designed preoperatively according to the CT data of jaw and dentition. 3D printed templates and occlusal splints are used to guide the costochondral graft and mandibular position. During surgery, the affected ramus is reconstructed with costochondral grafting under the virtual mandibular position. After surgery, the occlusal splint is fixed to maxilla at least one month, and then, replaced by orthodontic functional appliance to promote downward growth of the maxilla. Occlusion, facial symmetry, costochondral graft growing would be evaluated and analysed until adulthood.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • <12 years old
  • Unilateral temporomandibular joint ankylosis or condyle absence;
  • Temporomandibular joint reconstructed with costochondral graft;

Exclusion

Exclusion Criteria:

  • Bilateral temporomandibular joint ankylosis or condyle absence
  • Combined with systematic disease

Study Design

Total Participants: 15
Study Start date:
September 01, 2018
Estimated Completion Date:
December 31, 2024

Connect with a study center

  • Peking University Hospital of Stomatology

    Beijing, Beijing 100081
    China

    Active - Recruiting

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