An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial

Last updated: May 11, 2026
Sponsor: AbbVie
Overall Status: Active - Not Recruiting

Phase

3

Condition

Cancer/tumors

Non-hodgkin's Lymphoma

Bone Neoplasm

Treatment

Venetoclax

Clinical Study ID

NCT03844048
M19-388
2022-501522-38-00
  • All Genders

Study Summary

The purpose of this extension study is to provide venetoclax and obtain long-term safety data for subjects who continue to tolerate and derive benefit from receiving venetoclax in ongoing studies.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Subject has been enrolled and dosed in an ongoing venetoclax study and continues totolerate and derive benefit from the study drug.

  • Male subject agrees to refrain from sperm donation.

  • Female subjects must not be pregnant or breastfeeding.

Exclusion

Exclusion Criteria:

  • None.

Study Design

Total Participants: 165
Treatment Group(s): 1
Primary Treatment: Venetoclax
Phase: 3
Study Start date:
September 06, 2019
Estimated Completion Date:
August 31, 2027

Connect with a study center

  • Royal Prince Alfred Hospital /ID# 239557

    Camperdown, New South Wales 2050
    Australia

    Site Not Available

  • The Kinghorn Cancer Centre /ID# 241675

    Darlinghurst, New South Wales 2010
    Australia

    Site Not Available

  • St George Hospital /ID# 225589

    Kogarah, New South Wales 2217
    Australia

    Site Not Available

  • Liverpool Hospital /ID# 225591

    Liverpool, New South Wales 2170
    Australia

    Site Not Available

  • Royal Prince Alfred Hospital /ID# 239557

    Camperdown 2172563, New South Wales 2155400 2050
    Australia

    Site Not Available

  • St George Hospital /ID# 225589

    Kogarah 2161185, New South Wales 2155400 2217
    Australia

    Site Not Available

  • Liverpool Hospital /ID# 225591

    Liverpool 2159851, New South Wales 2155400 2170
    Australia

    Site Not Available

  • Peter MacCallum Cancer Ctr /ID# 210559

    Melbourne, Victoria 3000
    Australia

    Site Not Available

  • Peter MacCallum Cancer Ctr /ID# 210559

    Melbourne 2158177, Victoria 2145234 3000
    Australia

    Site Not Available

  • Fiona Stanley Hospital /ID# 239480

    Murdoch, Western Australia 6150
    Australia

    Site Not Available

  • Perth Blood Institute Ltd /ID# 225592

    Nedlands, Western Australia 6009
    Australia

    Site Not Available

  • Fiona Stanley Hospital /ID# 239480

    Murdoch 8349091, Western Australia 2058645 6150
    Australia

    Site Not Available

  • Perth Blood Institute Ltd /ID# 225592

    Nedlands 2064874, Western Australia 2058645 6009
    Australia

    Site Not Available

  • Medizinische Universitaet Graz /ID# 223817

    Graz, Steiermark 8010
    Austria

    Site Not Available

  • Duplicate_Medizinische Universitaet Graz /ID# 223817

    Graz, Styria 8010
    Austria

    Site Not Available

  • Duplicate_Medizinische Universitaet Graz /ID# 223817

    Graz 2778067, Styria 2764581 8010
    Austria

    Site Not Available

  • Cliniques Universitaires UCL Saint-Luc /ID# 224327

    Brussels, Brussels Capital 1200
    Belgium

    Site Not Available

  • Cliniques Universitaires UCL Saint-Luc /ID# 224327

    Brussels 2800866, Brussels Capital 2800867 1200
    Belgium

    Site Not Available

  • Cliniques Universitaires UCL Saint-Luc /ID# 224327

    Bruxelles, Bruxelles-Capitale 1200
    Belgium

    Site Not Available

  • Cliniques Universitaires UCL Saint-Luc /ID# 224327

    Woluwe-Saint-Lambert, Bruxelles-Capitale 1200
    Belgium

    Site Not Available

  • UCL Saint-Luc /ID# 224327

    Woluwe-Saint-Lambert, Bruxelles-Capitale 1200
    Belgium

    Site Not Available

  • CHUQ- Hôpital de l'Enfant-Jesus /ID# 224616

    Quebec City, Quebec G1J 1Z4
    Canada

    Site Not Available

  • CHUQ- Hôpital de l'Enfant-Jesus /ID# 224616

    Québec, Quebec G1J 1Z4
    Canada

    Site Not Available

  • CHUQ- Hôpital de l'Enfant-Jesus /ID# 224616

    Québec 6325494, Quebec 6115047 G1J 1Z4
    Canada

    Site Not Available

  • Rigshospitalet /ID# 224213

    Copenhagen Ø, Capital Region 2100
    Denmark

    Site Not Available

  • Aarhus Universitetshospital - Skejby /ID# 224214

    Aarhus, Central Jutland 8200
    Denmark

    Site Not Available

  • Aarhus Universitetshospital - Skejby /ID# 224214

    Aarhus 2624652, Central Jutland 6418539 8200
    Denmark

    Site Not Available

  • Herlev Hospital /ID# 224213

    Herlev, Hovedstaden 2730
    Denmark

    Site Not Available

  • Aarhus University Hospital /ID# 224214

    Aarhus N, Midtjylland 8200
    Denmark

    Site Not Available

  • CHRU Lille - Hôpital Claude Huriez /ID# 213509

    Lille CEDEX, Hauts-de-France 59045
    France

    Site Not Available

  • CHU Grenoble - Hopital Michallon /ID# 240497

    La Tronche, Isere 38700
    France

    Site Not Available

  • CHU Grenoble - Hopital Michallon /ID# 240497

    La Tronche 3006131, Isere 38700
    France

    Site Not Available

  • HCL - Hopital Lyon Sud /ID# 213508

    Pierre Benite CEDEX, Rhone 69495
    France

    Site Not Available

  • HCL - Hopital Lyon Sud /ID# 213508

    Pierre-Bénite, Rhone 69495
    France

    Site Not Available

  • HCL - Hopital Lyon Sud /ID# 213508

    Pierre-Bénite 2987314, Rhone 69495
    France

    Site Not Available

  • General Hospital of Athens Laiko /ID# 224087

    Athens, Attica 11527
    Greece

    Site Not Available

  • General Hospital of Athens Laiko /ID# 224087

    Athens 264371, Attica 6692632 11527
    Greece

    Site Not Available

  • General Hospital of Thessaloniki George Papanikolaou /ID# 224088

    Thessaloniki, 57010
    Greece

    Site Not Available

  • General Hospital of Thessaloniki George Papanikolaou /ID# 224088

    Thessaloniki 734077, 57010
    Greece

    Site Not Available

  • Queen Mary Hospital /ID# 224944

    Hong Kong, 999077
    Hong Kong

    Site Not Available

  • Queen Mary Hospital /ID# 224944

    Hong Kong 1819729, 999077
    Hong Kong

    Site Not Available

  • Beaumont Hospital /ID# 225165

    Beaumont, Dublin D09 XR63
    Ireland

    Site Not Available

  • Beaumont Hospital /ID# 225165

    Dublin, D09 XR63
    Ireland

    Site Not Available

  • Beaumont Hospital /ID# 225165

    Dublin 2964574, D09 XR63
    Ireland

    Site Not Available

  • Kobe City Medical Center General Hospital /ID# 241518

    Kobe-shi, Hyogo 650-0047
    Japan

    Site Not Available

  • Kobe City Medical Center General Hospital /ID# 241518

    Kobe, Hyōgo 650-0047
    Japan

    Site Not Available

  • Kobe City Medical Center General Hospital /ID# 241518

    Kobe 1859171, Hyōgo 1862047 650-0047
    Japan

    Site Not Available

  • Duplicate_National Hospital Organization Mito Medical Center /ID# 241986

    Higashi Ibaraki-gun, Ibaraki 311-3193
    Japan

    Site Not Available

  • National Hospital Organization Mito Medical Center /ID# 241986

    Higashi Ibaraki-gun, Ibaraki 311-3193
    Japan

    Site Not Available

  • Okayama Medical Center /ID# 241517

    Okayama-shi, Okayama 701-1192
    Japan

    Site Not Available

  • Duplicate_Okayama Medical Center /ID# 241517

    Okayama, Okayama-ken 701-1192
    Japan

    Site Not Available

  • Duplicate_Okayama Medical Center /ID# 241517

    Okayama 1854383, Okayama-ken 1854381 701-1192
    Japan

    Site Not Available

  • National Cancer Center Hospital /ID# 241516

    Chuo-ku, Tokyo 104-0045
    Japan

    Site Not Available

  • Samsung Medical Center /ID# 240882

    Seoul, Seoul Teugbyeolsi 06351
    Korea, Republic of

    Site Not Available

  • Centro de Investigacion Clínica Chapultepec SA de CV /ID# 227018

    Morelia, Michoacán 58260
    Mexico

    Site Not Available

  • Centro de Investigacion Clínica Chapultepec SA de CV /ID# 227018

    Morelia 3995402, Michoacán 3995955 58260
    Mexico

    Site Not Available

  • Hospital Universitario Dr. Jose Eleuterio Gonzalez /ID# 227017

    Monterrey, Nuevo León 64460
    Mexico

    Site Not Available

  • Hospital Universitario Dr. Jose Eleuterio Gonzalez /ID# 227017

    Monterrey 3995465, Nuevo León 3522542 64460
    Mexico

    Site Not Available

  • Aotearoa Clinical Trials /ID# 225596

    Papatoetoe, Auckland 2025
    New Zealand

    Site Not Available

  • Middlemore Clinical Trials /ID# 225596

    Papatoetoe, Auckland 2025
    New Zealand

    Site Not Available

  • North Shore Hospital /ID# 225597

    Takapuna, Auckland 0622
    New Zealand

    Site Not Available

  • Aotearoa Clinical Trials /ID# 225596

    Papatoetoe 6232008, Auckland 2193734 2025
    New Zealand

    Site Not Available

  • North Shore Hospital /ID# 225597

    Takapuna 2207740, Auckland 2193734 0622
    New Zealand

    Site Not Available

  • Wellington Regional Hospital /ID# 225593

    Newtown, Wellington Region 6021
    New Zealand

    Site Not Available

  • Wellington Regional Hospital /ID# 225593

    Newtown 6244789, Wellington Region 2179538 6021
    New Zealand

    Site Not Available

  • Middlemore Clinical Trials /ID# 225596

    Auckland, 2025
    New Zealand

    Site Not Available

  • Wellington Hospital (Capital and Coast District Health Board) /ID# 225593

    Wellington, 6021
    New Zealand

    Site Not Available

  • Duplicate_Pratia MCM Krakow /ID# 218561

    Krakow, Lesser Poland Voivodeship 30-727
    Poland

    Site Not Available

  • Duplicate_Pratia MCM Krakow /ID# 218561

    Krakow 3094802, Lesser Poland Voivodeship 858786 30-727
    Poland

    Site Not Available

  • Pratia MCM Krakow /ID# 218561

    Krakow, Malopolskie 30-727
    Poland

    Site Not Available

  • Instytut Hematologii i Transfuzjologii /ID# 225478

    Warsaw, Masovian Voivodeship 02-776
    Poland

    Site Not Available

  • Instytut Hematologii i Transfuzjologii /ID# 225478

    Warsaw 756135, Masovian Voivodeship 858787 02-776
    Poland

    Site Not Available

  • Instytut Hematologii i Transfuzjologii /ID# 225478

    Warszawa, Mazowieckie 02-776
    Poland

    Site Not Available

  • SP ZOZ Zespol Szpitali Miejskich w Chorzowie /ID# 225474

    Chorzów, Silesian Voivodeship 41-500
    Poland

    Site Not Available

  • SP ZOZ Zespol Szpitali Miejskich w Chorzowie /ID# 225474

    Chorzów 3101619, Silesian Voivodeship 3337497 41-500
    Poland

    Site Not Available

  • SP ZOZ Zespol Szpitali Miejskich w Chorzowie /ID# 225474

    Chorzow, Slaskie 41-500
    Poland

    Site Not Available

  • IPO Lisboa FG, EPE /ID# 225072

    Lisboa, 1099-023
    Portugal

    Site Not Available

  • IPO Lisboa FG, EPE /ID# 225072

    Lisbon, 1099-023
    Portugal

    Site Not Available

  • IPO Lisboa FG, EPE /ID# 225072

    Lisbon 2267057, 1099-023
    Portugal

    Site Not Available

  • Federal State Budgetary Scientific Institution N.N. Blokhin /ID# 225194

    Moscow, Moscow 115478
    Russia

    Site Not Available

  • Federal State Budgetary Scientific Institution N.N. Blokhin /ID# 225194

    Moscow 524901, Moscow 524894 115478
    Russia

    Site Not Available

  • Regional Oncological Dispensary /ID# 225195

    Penza, Penza Oblast 440071
    Russia

    Site Not Available

  • Regional Oncological Dispensary /ID# 225195

    Penza 511565, Penza Oblast 511555 440071
    Russia

    Site Not Available

  • Federal State Budgetary Scientific Institution N.N. Blokhin /ID# 225194

    Moscow, Moskva 115478
    Russian Federation

    Site Not Available

  • Regional Oncological Dispensary /ID# 225195

    Penza, Penzenskaya Oblast 440071
    Russian Federation

    Site Not Available

  • Samsung Medical Center /ID# 240882

    Seoul, Seoul Teugbyeolsi 06351
    South Korea

    Site Not Available

  • Samsung Medical Center /ID# 240882

    Seoul 1835848, Seoul Teugbyeolsi 06351
    South Korea

    Site Not Available

  • Hospital Universitario Fundacion Jimenez Diaz /ID# 225476

    Madrid, 28040
    Spain

    Site Not Available

  • Hospital Universitario Fundacion Jimenez Diaz /ID# 225476

    Madrid 3117735, 28040
    Spain

    Site Not Available

  • Skane University Hospital Lund /ID# 224747

    Lund, Skane Lan SE 221 41
    Sweden

    Site Not Available

  • Duplicate_Skane University Hospital Lund /ID# 224747

    Lund, Skåne County 221 41
    Sweden

    Site Not Available

  • Duplicate_Skane University Hospital Lund /ID# 224747

    Lund 2693678, Skåne County 3337385 221 41
    Sweden

    Site Not Available

  • National Taiwan University Hospital /ID# 224946

    Taipei City, Taipei 100
    Taiwan

    Site Not Available

  • China Medical University Hospital /ID# 224945

    Taichung, 40447
    Taiwan

    Site Not Available

  • China Medical University Hospital /ID# 224945

    Taichung 1668399, 40447
    Taiwan

    Site Not Available

  • China Medical University Hospital /ID# 224945

    Taichung City, 40447
    Taiwan

    Site Not Available

  • Ankara Univ Medical Faculty /ID# 225043

    Ankara, 06590
    Turkey

    Site Not Available

  • Istanbul University Istanbul Medical Faculty /ID# 225045

    Istanbul, 34093
    Turkey

    Site Not Available

  • Vehbi Koc vakfi Amerikan Hasta /ID# 225046

    Istanbul, 34365
    Turkey

    Site Not Available

  • Dokuz Eylul University Medical Faculty /ID# 225044

    Izmir, 35340
    Turkey

    Site Not Available

  • Ondokuz mayis University Facul /ID# 225042

    Samsun, 55200
    Turkey

    Site Not Available

  • Ankara Univ Medical Faculty /ID# 225043

    Ankara, 06590
    Turkey (Türkiye)

    Site Not Available

  • Ankara Univ Medical Faculty /ID# 225043

    Ankara 323786, 06590
    Turkey (Türkiye)

    Site Not Available

  • Istanbul University Istanbul Medical Faculty /ID# 225045

    Istanbul, 34093
    Turkey (Türkiye)

    Site Not Available

  • Vehbi Koc vakfi Amerikan Hasta /ID# 225046

    Istanbul, 34365
    Turkey (Türkiye)

    Site Not Available

  • Istanbul University Istanbul Medical Faculty /ID# 225045

    Istanbul 745044, 34093
    Turkey (Türkiye)

    Site Not Available

  • Vehbi Koc vakfi Amerikan Hasta /ID# 225046

    Istanbul 745044, 34365
    Turkey (Türkiye)

    Site Not Available

  • Municipal Non-Profit Enterprise City Clinical Hospital 4 of Dnipro City Council /ID# 240575

    Dnipro, 49102
    Ukraine

    Site Not Available

  • Municipal Non-Profit Enterprise City Clinical Hospital 4 of Dnipro City Council /ID# 240575

    Dnipro 709930, 49102
    Ukraine

    Site Not Available

  • University Hospitals Bristol NHS Foundation Trust /ID# 225162

    Bristol, Bristol, City Of BS1 3NU
    United Kingdom

    Site Not Available

  • Derriford Hospital and the Royal Eye Infirmary /ID# 218731

    Plymouth, Devon PL6 8DH
    United Kingdom

    Site Not Available

  • Derriford Hospital and the Royal Eye Infirmary /ID# 218731

    Plymouth 2640194, Devon PL6 8DH
    United Kingdom

    Site Not Available

  • Leicester Royal Infirmary /ID# 240468

    Leicester, England LE1 5WW
    United Kingdom

    Site Not Available

  • Leicester Royal Infirmary /ID# 240468

    Leicester 2644668, England 6269131 LE1 5WW
    United Kingdom

    Site Not Available

  • Kings College Hospital NHS Foundation Trust /ID# 218735

    London, Greater London SE5 9RS
    United Kingdom

    Site Not Available

  • UCLH NHS Foundation Trust - University College Hospital /ID# 240467

    London, Greater London NW1 2PG
    United Kingdom

    Site Not Available

  • University College London Hospital /ID# 240467

    London, Greater London NW1 2BU
    United Kingdom

    Site Not Available

  • University College London Hospitals NHS Foundation Trust /ID# 240467

    London, Greater London NW1 2PG
    United Kingdom

    Site Not Available

  • Kings College Hospital NHS Foundation Trust /ID# 218735

    London 2643743, Greater London SE5 9RS
    United Kingdom

    Site Not Available

  • University College London Hospital /ID# 240467

    London 2643743, Greater London NW1 2BU
    United Kingdom

    Site Not Available

  • University Hospital Southampton NHS Foundation Trust /ID# 225161

    Southampton, Hampshire SO16 6YD
    United Kingdom

    Site Not Available

  • University Hospital Southampton NHS Foundation Trust /ID# 225161

    Southampton 2637487, Hampshire SO16 6YD
    United Kingdom

    Site Not Available

  • Blackpool Teaching Hospitals NHS Foundation Trust /ID# 225163

    Blackpool, FY3 8NR
    United Kingdom

    Site Not Available

  • Blackpool Teaching Hospitals NHS Foundation Trust /ID# 225163

    Blackpool 2655459, FY3 8NR
    United Kingdom

    Site Not Available

  • Clatterbridge Cancer Centre - Liverpool /ID# 218736

    Liverpool, L7 8YA
    United Kingdom

    Site Not Available

  • The Clatterbridge Cancer Centre NHS Foundation Trust /ID# 218736

    Liverpool, L7 8YA
    United Kingdom

    Site Not Available

  • Clatterbridge Cancer Centre - Liverpool /ID# 218736

    Liverpool 2644210, L7 8YA
    United Kingdom

    Site Not Available

  • King's College Hospital NHS Foundation Trust /ID# 218735

    London, SE5 9RS
    United Kingdom

    Site Not Available

  • University Hospital Plymouth NHS Trust /ID# 218731

    Plymouth, PL6 5FP
    United Kingdom

    Site Not Available

  • The Royal Wolverhampton NHS Trust /ID# 225164

    Wolverhampton, WV10 0QP
    United Kingdom

    Site Not Available

  • The Royal Wolverhampton NHS Trust /ID# 225164

    Wolverhampton 2633691, WV10 0QP
    United Kingdom

    Site Not Available

  • University of Arizona Cancer Center - Tucson /ID# 210548

    Tucson, Arizona 85724
    United States

    Site Not Available

  • University of Arizona Cancer Center - Tucson /ID# 210548

    Tucson 5318313, Arizona 5551752 85724
    United States

    Site Not Available

  • UCLA Santa Monica Hematology Oncology /ID# 210551

    Los Angeles, California 90095
    United States

    Site Not Available

  • UCLA Santa Monica Hematology Oncology /ID# 210551

    Los Angeles 5368361, California 5332921 90095
    United States

    Site Not Available

  • Ingalls Memorial Hosp /ID# 210553

    Harvey, Illinois 60426
    United States

    Site Not Available

  • Ingalls Memorial Hosp /ID# 210553

    Harvey 4895298, Illinois 4896861 60426
    United States

    Site Not Available

  • Dana-Farber Cancer Institute /ID# 215360

    Boston, Massachusetts 02215
    United States

    Site Not Available

  • Dana-Farber Cancer Institute /ID# 215360

    Boston 4930956, Massachusetts 6254926 02215
    United States

    Site Not Available

  • University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 231132

    Ann Arbor, Michigan 48109
    United States

    Site Not Available

  • Henry Ford Health System /ID# 210557

    Detroit, Michigan 48202
    United States

    Site Not Available

  • University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 231132

    Ann Arbor 4984247, Michigan 5001836 48109
    United States

    Site Not Available

  • Dartmouth-Hitchcock Medical Center - 1 Medical Center Drive /ID# 210555

    Lebanon, New Hampshire 03756
    United States

    Site Not Available

  • Dartmouth-Hitchcock Medical Center /ID# 210555

    Lebanon, New Hampshire 03756
    United States

    Site Not Available

  • Dartmouth-Hitchcock Medical Center /ID# 210555

    Lebanon 5088597, New Hampshire 5090174 03756
    United States

    Site Not Available

  • Memorial Sloan Kettering Cancer Center /ID# 210549

    New York, New York 10065-6007
    United States

    Site Not Available

  • Duplicate_Gabrail Cancer Center Research /ID# 212061

    Canton, Ohio 44718
    United States

    Site Not Available

  • Gabrail Cancer Center Research /ID# 212061

    Canton, Ohio 44718
    United States

    Site Not Available

  • Swedish Cancer Institute - Edmonds /ID# 213120

    Seattle, Washington 98104
    United States

    Site Not Available

  • Swedish Cancer Institute /ID# 213120

    Seattle, Washington 98104-3588
    United States

    Site Not Available

  • Swedish Medical Center - Seattle /ID# 213120

    Seattle, Washington 98104
    United States

    Site Not Available

  • Swedish Cancer Institute /ID# 213120

    Seattle 5809844, Washington 5815135 98104-3588
    United States

    Site Not Available

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