Phase
Condition
Parkinson's Disease
Memory Problems
Dyskinesias
Treatment
MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)
Clinical Study ID
Ages > 50 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Veterans who seek services at Hines VA Hospital or Jesse Brown VA Medical Center
Diagnosis of PD or atypical parkinsonism as determined by a neurologist
Meet criteria for having mild cognitive impairment
Receiving stable (i.e., no changes in medication and medication dose) medication andwho are expected to remain on stable medication for the duration of the RCT
Speak and read English
50 years or older
Exclusion
Exclusion Criteria:
Dementia
Failure to demonstrate decision making capacity
History of deep brain stimulation surgery
Severe depression
Resting head tremor
Dyskinesia that will interfere with collecting imaging data
Has congestive heart failure
Implanted cardiac pacemaker or defibrillator
Cochlear implant, nerve stimulator, or intracranial metal clips
Implanted medical pump
Increased intracranial pressure
History of claustrophobia
Metal in eyes/face, shrapnel/bullet remnants in brain
Participants at potential increased risk of seizure including those who have thefollowing:
history (or family history) of seizure or epilepsy
history of stroke, head injury, or unexplained seizures
presence of other neurological disease that may be associated with an alteredseizure threshold
such as CVA, cerebral aneurysm, dementia, increased intracranial pressure
Concurrent medication use such as tricyclic antidepressants, neurolepticmedications, any other drug known to lower seizure threshold
Secondary conditions that may significantly alter electrolyte balance or lowerseizure threshold
No quantifiable motor threshold such that rTMS dosage cannot be accuratelydeter-mined
Study Design
Study Description
Connect with a study center
Jesse Brown VA Medical Center, Chicago, IL
Chicago, Illinois 60612
United StatesSite Not Available
Edward Hines Jr. VA Hospital, Hines, IL
Hines, Illinois 60141-3030
United StatesActive - Recruiting
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