TheEffect of pH on Misoprostol in Induction of Labor

Last updated: May 16, 2020
Sponsor: Aljazeera Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Acute Pain

Treatment

N/A

Clinical Study ID

NCT03829592
Misoprostol
  • Ages 20-42
  • Female
  • Accepts Healthy Volunteers

Study Summary

Misoprostol is a synthetic analogue of the naturally occurring prostaglandin E1. It was initially marketed for the treatment of peptic ulcers due to its mucosal protective and anti-secretory properties, but has commonly been used for the induction of abortion and labour .

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Singleton pregnancies. Gestational age 38-41 weeks. Cephalic presentation

Exclusion

Exclusion Criteria:

    1. Multi-fetal pregnancy. 2. Pregnant women less than 38 weeks gestation.

Study Design

Total Participants: 180
Study Start date:
February 06, 2019
Estimated Completion Date:
July 12, 2020

Study Description

Although initially having been established for oral use, misoprostol tablets are commonly used as vaginal suppositories for the previously purposes. Water or saline are frequently used in common practice to moisten the tablets prior to their administration, however, according to the pharmacokinetics of the drug, it should liquefy better in an acidic medium

Connect with a study center

  • Algazeerah and Kasralainy hospital

    Giza,
    Egypt

    Active - Recruiting

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