A Registry for Patients With Multifocal Ground Glass Opacities (GGOs)

Last updated: December 16, 2024
Sponsor: Memorial Sloan Kettering Cancer Center
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT03802981
18-541
  • Ages > 19
  • All Genders

Study Summary

The purpose of this registry study is to actively monitor people with GGOs and collect information about them, so that investigators can learn more about these lesions and about the risk of developing lung cancer in study participants whose GGOs are being monitored in the active surveillance program.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age greater than 18 years

  • Have two or more GGOs on initial CT imaging

  • GGOs must be measure ≤3.0 cm and ≥0.6 cm in the greatest dimension

  • GGOs must be greater than half ground glass

A biopsy is not necessary for inclusion in the trial. Biopsy of a GGO, even with a diagnosis of adenocarcinoma, does not necessarily preclude enrollment in this surveillance protocol. In other words, patients with a diagnosis of adenocarcinoma are still eligible, at the discretion of the clinician and/or investigator, if they meet the above criteria.

Exclusion

Exclusion Criteria:

  • Patients who are actively undergoing lung cancer treatment or have a history of lungcancer, except for cases of completely resected pathologic stage IA nonsmall celllung cancer (NSCLC). Patients with stage IA NSCLC and multiple GGOs can enroll inthis active surveillance protocol after complete resection of the NSCLC andconfirmation of stage on final pathologic assessment.

  • The presence of any solid lesion ≥0.6 cm suspicious for malignancy.

  • Patients who are actively undergoing treatment for other malignancies

Study Design

Total Participants: 338
Study Start date:
January 09, 2019
Estimated Completion Date:
January 31, 2026

Connect with a study center

  • McMaster University (Data Collection Only)

    Hamilton, Ontario L8N 3Z5
    Canada

    Site Not Available

  • University Health Network

    Toronto, Ontario M5G 2C4
    Canada

    Site Not Available

  • Centre Hospitalier de l'Université de Montreal

    Montréal, Quebec H2L 4M1
    Canada

    Site Not Available

  • University of California San Diego

    San Diego, California 92103
    United States

    Site Not Available

  • Stanford University Medical Center (Data collection only)

    Stanford, California 94305-5408
    United States

    Site Not Available

  • Hartford Healthcare

    Hartford, Connecticut 06102
    United States

    Site Not Available

  • Rush University Medical Center (Data collection only)

    Chicago, Illinois 606012
    United States

    Site Not Available

  • Brigham and Women's Hospital

    Boston, Massachusetts 02115
    United States

    Site Not Available

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts 02114
    United States

    Site Not Available

  • University of Michigan

    Ann Arbor, Michigan 48109
    United States

    Site Not Available

  • Mayo Clinic

    Rochester, Minnesota 55905
    United States

    Site Not Available

  • George Washington University School of Medicine

    Saint Louis, Missouri 63110
    United States

    Site Not Available

  • Washington University School of Medicine

    Saint Louis, Missouri 63110
    United States

    Site Not Available

  • Memorial Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey 07920
    United States

    Site Not Available

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey 07748
    United States

    Site Not Available

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey 07645
    United States

    Site Not Available

  • Roswell Park Cancer Institute (Data Collection Only)

    Buffalo, New York 14263-0001
    United States

    Site Not Available

  • Memorial Sloan Kettering Commack

    Commack, New York 11725
    United States

    Site Not Available

  • Memorial Sloan Kettering Westchester

    Harrison, New York 10604
    United States

    Site Not Available

  • Memorial Sloan Kettering Cancer Center Hauppauge

    Hauppauge, New York 11788
    United States

    Site Not Available

  • Memorial Sloan Kettering Cancer Center

    New York, New York 10065
    United States

    Site Not Available

  • New York Presbyterian Hospital

    New York, New York 10065
    United States

    Site Not Available

  • Memorial Sloan Kettering Rockville Centre

    Rockville Centre, New York 11570
    United States

    Site Not Available

  • Memorial Sloan Kettering Nassau

    Uniondale, New York 11553
    United States

    Site Not Available

  • Duke University Medical Center

    Durham, North Carolina 27701
    United States

    Site Not Available

  • Lehigh Valley Health Network

    Allentown, Pennsylvania 18103
    United States

    Site Not Available

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania 19111
    United States

    Site Not Available

  • Temple University

    Philadelphia, Pennsylvania 19140
    United States

    Site Not Available

  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania 19107
    United States

    Site Not Available

  • University of Pennsylvania (Data Collection Only)

    Philadelphia, Pennsylvania 19104
    United States

    Site Not Available

  • Allegheny Health Network

    Pittsburgh, Pennsylvania 15212
    United States

    Site Not Available

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania 15213
    United States

    Site Not Available

  • Baylor University Medical Center

    Houston, Texas 77030
    United States

    Site Not Available

  • MD Anderson Cancer Center

    Houston, Texas 77030-4009
    United States

    Site Not Available

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