Clinical Evaluation of Acupuncture Treatment for Negative Symptoms of Schizophrenia

Last updated: January 11, 2019
Sponsor: Shanghai Mental Health Center
Overall Status: Active - Enrolling

Phase

4

Condition

Tourette's Syndrome

Mood Disorders

Psychosis

Treatment

N/A

Clinical Study ID

NCT03802838
ZHYY-ZXYJHZX-2-201708
  • Ages 18-60
  • All Genders

Study Summary

To explore the effects of combined traditional Chinese and Western medicine( Chinese acupuncture combined with Amisulpride Tablets) on negative symptoms, cognitive function and social function in patients with schizophrenia, and the side effects and safety of Chinese acupuncture combined with Amisulpride Tablets.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • The diagnosis of schizophrenia according to International classificationdiagnosis-10(ICD-10)

  • patients at an age between 18～60 years old of Han nationality

Exclusion

Exclusion Criteria:

  • other psychiatric diagnoses

  • Suffering from serious physical disease and can not accept the treatment

  • Patients to be diagnosed according to ICD-10 for substance abused, development delayed

  • Inability to sign informed consent because of capacity due due to severe mentalillness, significant psychomotor agitation or slowness test completion

  • claustrophobic

  • metal implantation in vivo

Study Design

Total Participants: 50
Study Start date:
October 01, 2017
Estimated Completion Date:
September 30, 2019

Study Description

Our research hypothesis：1. Medically assisted Acupuncture in schizophrenia can improve negative symptoms；2. Drug assisted Acupuncture Therapy has better cognitive function in schizophrenic patients than single drug；3. Schizophrene with acupuncture have fewer and lighter adverse reactions。This study was carried out only in Shanghai Mental Health Center. It was a parallel randomized study.Schizophrene with negative symptoms were treated with atypical antipsychotic drug amisulpride, but still remained negative symptoms. Using the mature Chinese medicine therapy acupuncture auxiliary treatment, using the more reliable clinical evaluation method (the grader blind method: The raters were not sure which patients were the study group or the control group), compared with the single drug treatment, To observe the changes of negative symptoms and cognitive function, and the incidence of adverse reactions of acupuncture therapy, to explore the "new" auxiliary means for the treatment of negative symptoms, to guide clinical individualization and accurate medical treatment.

Connect with a study center

  • Shanghai Mental Health Center

    Shanghai, Shanghai 200030
    China

    Site Not Available

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