Multi-Treatment PNN Modulation for Chronic Rhinitis

Inclusion Criteria:

• Presence of moderate to severe rhinorrhea symptoms and mild to severe nasal congestionsymptoms for >3 months.

• Documented allergy test within the last 10 years that defines whether or not subjecthas allergies to perennial and seasonal allergens, or is willing to have one performedprior to study exit.

• Able to provide informed consent and willing to complete study activities and visitsper protocol.

Exclusion Criteria:

• Clinically significant anatomic obstructions that limit access to the posterior nose.

• Prior sinus or nasal surgery that significantly alters the anatomy of the posteriornose.

• Moderate to severe ocular symptoms as determined.

• History of epistaxis in the past 3 months.

• History of rhinitis medicamentosa.

• Prior head or neck irradiation.

• Active or chronic nasal or sinus infection.

• Pregnant.

• Allergy or intolerance to anesthetic agent.

• Cryoglobulinemia, paroxysmal cold hemoglobinuria, cold urticaria, Raynaud's disease,and/or, open and/or infected wounds at or near the target tissue.

• Currently participating in another clinical research study.

• Any physical condition that, in the investigator's opinion, would prevent adequatestudy participation or pose increased risk.