Electroacupuncture and Solifenacin for Urgency-predominant Mixed Urinary Incontinence

Inclusion Criteria:

1. Female patients diagnosed with mixed urinary incontinence in accordance with EAUguideline by history intaking and physical examination[8];
2. Age between 18 and 80 years old;
3. Urgency index greater than stress index by MESA questionnaire[12];
4. At least 4 episodes of urgency urinary incontinence in 72-hour voiding diary;
5. With MUI for at least 3 months, and more than 50% of the total incontinence episodesis urgency one in 72-hour voiding diary;
6. Positive cough test;
7. A voluntarily-signed written informed content.

Exclusion Criteria:

1. Having pure stress urinary incontinence, pure urgency urinary incontinence, overflowurinary incontinence or neurogenic bladder;
2. Uncontrolled urinary tract infection;
3. Tumor in urinary system or pelvic organs;
4. Pelvic organ prolapse≥degreeⅡ;
5. Residual urine volume≥100ml;
6. Maximum flow rate<15ml/s;
7. Treated incontinence by acupuncture or positive medications, such as antimuscarinicdrug within the past 1 month;
8. Underwent surgery of anti-incontinence or in pelvic area, metrectomy included;
9. Complication of uncontrolled diabetes and severe hypertension;
10. Complicated diseases in nerves system that could hamper hypourethral function, such asMultiple sclerosis, senile dementia, Parkinson's disease, spinal cord injury, caudaequina nerve injury and multiple system atrophy;
11. Severe complications in cardiac, lungs, cerebrum, hepar, renal system, psychonosologyand coagulation function, or obvious cognitive disability;
12. Installed a cardiac pacemaker;
13. Allergic to solifenacin or with contraindications to antimuscarinic drug, like urinaryretention, gastrointestinal peristalsis paralysis, myasthenia gravis, ulcerativecolitis, angle-closure glaucoma;
14. Allergic to metal or intolerant to the stimulation of electroacupuncture;
15. Already with child or plan to conceive in the future 1 year, or within 1 year afterdelivery.