Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1

Last updated: May 22, 2025
Sponsor: Mirati Therapeutics Inc.
Overall Status: Active - Recruiting

Phase

1/2

Condition

Neoplasm Metastasis

Metastatic Cancer

Neoplasms

Treatment

Cetuximab

Afatinib

MRTX849

Clinical Study ID

NCT03785249
CA239-0008
849-001
CA239-0008
  • Ages > 18
  • All Genders

Study Summary

This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors that have a KRAS G12C mutation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Histologically confirmed diagnosis of a solid tumor malignancy with KRAS G12Cmutation

  • Unresectable or metastatic disease

  • Standard treatment is not available or patient declines; first-line treatment forNSCLC for certain cohorts

  • Adequate organ function

Exclusion

Exclusion Criteria:

  • History of intestinal disease or major gastric surgery or inability to swallow oralmedications

  • Other active cancer

Study Design

Total Participants: 822
Treatment Group(s): 4
Primary Treatment: Cetuximab
Phase: 1/2
Study Start date:
January 15, 2019
Estimated Completion Date:
January 16, 2026

Study Description

This study will evaluate the safety, tolerability, pharmacokinetics, metabolites, pharmacodynamics, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors with a KRAS G12C mutation. MRTX849 (adagrasib) is an orally-available small molecule inhibitor of KRAS G12C.

Connect with a study center

  • PanOncology Trials

    San Juan, 00935
    Puerto Rico

    Active - Recruiting

  • PanOncology Trials - Rio Piedras Medical Center

    San Juan, 00935
    Puerto Rico

    Active - Recruiting

  • ONeal Comprehensive Cancer Center at the University of Alabama at Birmingham

    Birmingham, Alabama 35294
    United States

    Active - Recruiting

  • University of Alabama at Birmingham

    Birmingham, Alabama 35294
    United States

    Completed

  • Alaska Oncology and Hematology

    Anchorage, Alaska 99508
    United States

    Active - Recruiting

  • Mayo Clinic Arizona - Phoenix Campus

    Phoenix, Arizona 85054
    United States

    Active - Recruiting

  • Mayo Clinic in Arizona

    Phoenix, Arizona 85054
    United States

    Active - Recruiting

  • Local Institution - 001-807

    Scottsdale, Arizona 85258
    United States

    Site Not Available

  • Arizona Oncology Associates

    Tucson, Arizona 85704
    United States

    Active - Recruiting

  • Local Institution - 001-873-A

    Tucson, Arizona 85704
    United States

    Site Not Available

  • USOR - Arizona Oncology - Tucson - Rudasill

    Tucson, Arizona 85704
    United States

    Active - Recruiting

  • Kaiser Permanente-Bellflower Medical Offices

    Bellflower, California 90706
    United States

    Site Not Available

  • Local Institution - 001-840-B

    Bellflower, California 90706
    United States

    Site Not Available

  • Beverly Hills Cancer Center

    Beverly Hills, California 90211
    United States

    Active - Recruiting

  • City of Hope

    Duarte, California 91010
    United States

    Active - Recruiting

  • City of Hope - Duarte (Main Campus)

    Duarte, California 91010
    United States

    Active - Recruiting

  • Local Institution - 001-850-K

    Dublin, California 94568
    United States

    Site Not Available

  • Providence Medical Foundation - Virginia K. Crosson Cancer Center - Fullerton

    Fullerton, California 92835
    United States

    Active - Recruiting

  • St. Joseph Heritage Healthcare

    Fullerton, California 92835
    United States

    Active - Recruiting

  • Local Institution - 001-840-C

    Harbor City, California 90710
    United States

    Site Not Available

  • University of California San Diego Moores Cancer Center

    La Jolla, California 92093
    United States

    Active - Recruiting

  • Cancer & Blood Specialty Clinic

    Los Alamitos, California 90720
    United States

    Active - Recruiting

  • TRIO - Cancer and Blood Specialty Clinic

    Los Alamitos, California 90720
    United States

    Active - Recruiting

  • Southern California Permanente Medical Group - Los Angeles Medical Center

    Los Angeles, California 90027
    United States

    Active - Recruiting

  • Valkyrie Clinical Trials

    Los Angeles, California 90067
    United States

    Active - Recruiting

  • Hoag Memorial Hospital Presbyterian

    Newport Beach, California 92663
    United States

    Active - Recruiting

  • Hoag Memorial Hospital Presbyterian - Newport Beach

    Newport Beach, California 92663
    United States

    Active - Recruiting

  • Local Institution - 001-850-B

    Oakland, California 94611
    United States

    Site Not Available

  • University of California Irvine Medical Center

    Orange, California 92868
    United States

    Active - Recruiting

  • University of California, Irvine

    Orange, California 92868
    United States

    Active - Recruiting

  • Local Institution - 001-850-C

    Roseville, California 95661
    United States

    Site Not Available

  • Local Institution - 001-850-D

    Sacramento, California 95825
    United States

    Site Not Available

  • Local Institution - 001-850-J

    Sacramento, California 95814
    United States

    Site Not Available

  • California Cancer Associates for Research and Excellence

    San Diego, California 92111
    United States

    Active - Recruiting

  • California Cancer Associates for Research and Excellence (cCARE) - San Diego 4S Ranch

    San Diego, California 92111
    United States

    Active - Recruiting

  • Local Institution - 001-840-A

    San Diego, California 92120
    United States

    Site Not Available

  • Local Institution - 001-850-E

    San Francisco, California 94115
    United States

    Site Not Available

  • Local Institution - 001-850-H

    San Francisco, California 94080
    United States

    Site Not Available

  • Local Institution - 001-850-F

    San Jose, California 95119
    United States

    Site Not Available

  • Local Institution - 001-850-A

    San Leandro, California 94577
    United States

    Site Not Available

  • Ridley - Tree Cancer Center - Santa Barbara

    Santa Barbara, California 93105
    United States

    Active - Recruiting

  • Local Institution - 001-850-I

    Santa Clara, California 95051
    United States

    Site Not Available

  • Local Institution - 001-884-A

    Solvang, California 93463
    United States

    Site Not Available

  • Kaiser Permanente

    Vallejo, California 94589
    United States

    Active - Recruiting

  • Kaiser Permanente - Vallejo Medical Center

    Vallejo, California 94589
    United States

    Active - Recruiting

  • Local Institution - 001-850-G

    Walnut Creek, California 94596
    United States

    Site Not Available

  • Local Institution - 001-872

    Aurora, Colorado 80012
    United States

    Site Not Available

  • Rocky Mountain Cancer Centers

    Aurora, Colorado 80012
    United States

    Active - Recruiting

  • UCHealth Cancer Care - Anschutz Medical Campus - University of Colorado Cancer Center

    Aurora, Colorado 80045
    United States

    Active - Recruiting

  • USOR - Rocky Mountain Cancer Centers - Aurora

    Aurora, Colorado 80012
    United States

    Active - Recruiting

  • University of Colorado Hospital

    Aurora, Colorado 80045
    United States

    Active - Recruiting

  • Local Institution - 001-872-H

    Boulder, Colorado 80303
    United States

    Site Not Available

  • Local Institution - 001-872-E

    Colorado Springs, Colorado 80907
    United States

    Site Not Available

  • Local Institution - 001-872-L

    Colorado Springs, Colorado 80920
    United States

    Site Not Available

  • Local Institution - 001-872-B

    Denver, Colorado 80218
    United States

    Site Not Available

  • Local Institution - 001-951 - A

    Denver, Colorado 80218
    United States

    Site Not Available

  • Local Institution - 001-951 - B

    Denver, Colorado 80218
    United States

    Site Not Available

  • SCL Health - Saint Joseph Hospital Cancer Center

    Denver, Colorado 80218
    United States

    Site Not Available

  • Cancer Centers of Colorado - St. Marys Regional Hospital

    Grand Junction, Colorado 81501
    United States

    Active - Recruiting

  • St. Mary's Hospital & Regional Medical Center - Research

    Grand Junction, Colorado 81501
    United States

    Site Not Available

  • SCL Health - Saint Joseph Hospital Cancer Center

    Lafayette, Colorado 80026
    United States

    Active - Recruiting

  • Local Institution - 001-872-A

    Lakewood, Colorado 80228
    United States

    Site Not Available

  • Local Institution - 001-872-D

    Littleton, Colorado 80218
    United States

    Site Not Available

  • Local Institution - 001-872-K

    Lone Tree, Colorado 80124
    United States

    Site Not Available

  • Local Institution - 001-872-C

    Longmont, Colorado 80501
    United States

    Site Not Available

  • Local Institution - 001-872-J

    Parker, Colorado 80138
    United States

    Site Not Available

  • Local Institution - 001-872-F

    Pueblo, Colorado 81008
    United States

    Site Not Available

  • Local Institution - 001-872-G

    Pueblo, Colorado 81008
    United States

    Site Not Available

  • Local Institution - 001-872-I

    Thornton, Colorado 80260
    United States

    Site Not Available

  • Yale Cancer Center

    New Haven, Connecticut 06510
    United States

    Active - Recruiting

  • Medical Oncology Hematology Consultants

    Newark, Delaware 19713
    United States

    Active - Recruiting

  • USOR - Medical Oncology Hematology Consultants

    Newark, Delaware 19713-2055
    United States

    Active - Recruiting

  • Local Institution - 001-929i

    Altamonte Springs, Florida 32701
    United States

    Site Not Available

  • Boca Raton Clinical Research Associates, Inc.

    Boca Raton, Florida 33432
    United States

    Active - Recruiting

  • Local Institution - 001-922A

    Bonita Springs, Florida 34135
    United States

    Site Not Available

  • Local Institution - 001-922D

    Bradenton, Florida 34211
    United States

    Site Not Available

  • Local Institution - 001-929c

    Brandon, Florida 33511
    United States

    Site Not Available

  • Local Institution - 001-922E

    Cape Coral, Florida 33909
    United States

    Site Not Available

  • Local Institution - 001-929g

    Clearwater, Florida 33761
    United States

    Site Not Available

  • Local Institution - 001-926b

    Daytona Beach, Florida 32117
    United States

    Site Not Available

  • Local Institution - 001-922B

    Fort Myers, Florida 33905
    United States

    Site Not Available

  • Local Institution - 001-922C

    Fort Myers, Florida 33908
    United States

    Site Not Available

  • SCRI - Florida Cancer Specialists - South Region Research Office

    Fort Myers, Florida 33901
    United States

    Active - Recruiting

  • SCRI - Florida Cancer Specialists- South

    Fort Myers, Florida 33901
    United States

    Active - Recruiting

  • Local Institution - 001-929b

    Gainesville, Florida 32605
    United States

    Site Not Available

  • Mayo Clinic - Jacksonville

    Jacksonville, Florida 32224
    United States

    Active - Recruiting

  • Mayo Clinic in Florida

    Jacksonville, Florida 32224
    United States

    Active - Recruiting

  • Local Institution - 001-929m

    Lady Lake, Florida 32159
    United States

    Site Not Available

  • Local Institution - 001-929e

    Largo, Florida 33770
    United States

    Site Not Available

  • Local Institution - 001-929n

    Lecanto, Florida 34461
    United States

    Site Not Available

  • Miami Cancer Institute

    Miami, Florida 33176
    United States

    Active - Recruiting

  • Miami Cancer Institute Baptist Health

    Miami, Florida 33176
    United States

    Active - Recruiting

  • Mount Sinai Comprehensive Cancer Center

    Miami Beach, Florida 33140
    United States

    Active - Recruiting

  • Local Institution - 001-922F

    Naples, Florida 34102
    United States

    Site Not Available

  • Local Institution - 001-922G

    Naples, Florida 34102
    United States

    Site Not Available

  • Florida Cancer Affiliates - Ocala

    Ocala, Florida 34471
    United States

    Active - Recruiting

  • Florida Cancer Affiliates - Ocala - Main

    Ocala, Florida 34474
    United States

    Active - Recruiting

  • Local Institution - 001-929p

    Ocala, Florida 34474
    United States

    Site Not Available

  • Local Institution - 001-929j

    Orange City, Florida 32763
    United States

    Site Not Available

  • Mid Florida Cancer Centers - Orange City

    Orange City, Florida 32763
    United States

    Active - Recruiting

  • Mid Florida Hematology and Oncology Center

    Orange City, Florida 37263
    United States

    Active - Recruiting

  • Local Institution - 001-929l

    Orlando, Florida 32806
    United States

    Site Not Available

  • Woodlands Medical Specialists

    Pensacola, Florida 32503
    United States

    Active - Recruiting

  • BRCR Medical Center

    Plantation, Florida 33322
    United States

    Site Not Available

  • Local Institution - 001-922H

    Port Charlotte, Florida 33980
    United States

    Site Not Available

  • Local Institution - 001-929a

    Saint Petersburg, Florida 33705
    United States

    Site Not Available

  • SCRI - Florida Cancer Specialists - North Region Research Office

    Saint Petersburg, Florida 33705
    United States

    Active - Recruiting

  • SCRI - Florida Cancer Specialists-North

    Saint Petersburg, Florida 33705
    United States

    Active - Recruiting

  • Local Institution - 001-922I

    Sarasota, Florida 34232
    United States

    Site Not Available

  • Local Institution - 001-922J

    Sarasota, Florida 34236
    United States

    Site Not Available

  • Local Institution - 001-929h

    Spring Hill, Florida 34608
    United States

    Site Not Available

  • Local Institution - 001-926d

    Stuart, Florida 34994
    United States

    Site Not Available

  • Local Institution - 001-929d

    Tampa, Florida 33607
    United States

    Site Not Available

  • Local Institution - 001-929k

    Tavares, Florida 32778
    United States

    Site Not Available

  • Local Institution - 001-929f

    Trinity, Florida 34655
    United States

    Site Not Available

  • Local Institution - 001-922K

    Venice, Florida 34285
    United States

    Site Not Available

  • Local Institution - 001-922L

    Venice, Florida 34292
    United States

    Site Not Available

  • Local Institution - 001-926c

    Vero Beach, Florida 32960
    United States

    Site Not Available

  • Local Institution - 001-926a

    Wellington, Florida 33414
    United States

    Site Not Available

  • SCRI - Florida Cancer Specialists - East Region Research Office

    West Palm Beach, Florida 33401
    United States

    Active - Recruiting

  • SCRI - Florida Cancer Specialists- East

    West Palm Beach, Florida 33401
    United States

    Active - Recruiting

  • Local Institution - 001-929o

    Winter Park, Florida 32789
    United States

    Site Not Available

  • University Cancer & Blood Center (UCBC) - Athens

    Athens, Georgia 30607
    United States

    Active - Recruiting

  • University Cancer and Blood Center

    Athens, Georgia 30607
    United States

    Active - Recruiting

  • Local Institution - 001-835-C

    Austell, Georgia 30106
    United States

    Site Not Available

  • Local Institution - 001-835-E

    Austell, Georgia 30106
    United States

    Site Not Available

  • Local Institution - 001-835-D

    Carrollton, Georgia 30117
    United States

    Site Not Available

  • Local Institution - 001-835-F

    Carrollton, Georgia 30117
    United States

    Site Not Available

  • Local Institution - 001-835-A

    Cartersville, Georgia 30121
    United States

    Site Not Available

  • Local Institution - 001-835-B

    Douglasville, Georgia 30134
    United States

    Site Not Available

  • Northwest Georgia Oncology Centers Wellstar - Marietta

    Marietta, Georgia 30060
    United States

    Active - Recruiting

  • Northwest Georgia Oncology Centers, PC

    Marietta, Georgia 30060
    United States

    Active - Recruiting

  • Local Institution - 001-828

    Chicago, Illinois 60611
    United States

    Site Not Available

  • Affiliated Oncologists - Millenium Medical Center

    Chicago Ridge, Illinois 60415
    United States

    Active - Recruiting

  • Affiliated Oncologists - Millenium Medical Center - Chicago Ridge

    Chicago Ridge, Illinois 60415
    United States

    Active - Recruiting

  • Affiliated Oncologists, LLC

    Chicago Ridge, Illinois 60415
    United States

    Active - Recruiting

  • Illinois Cancer Specialists - Niles

    Niles, Illinois 60714
    United States

    Active - Recruiting

  • USOR - Illinois Cancer Specialists - Niles

    Niles, Illinois 60714
    United States

    Active - Recruiting

  • Memorial Hospital

    South Bend, Indiana 46601
    United States

    Active - Recruiting

  • Memorial Hospital South Bend

    South Bend, Indiana 46601
    United States

    Active - Recruiting

  • Local Institution - 001-831

    Iowa City, Iowa 52242
    United States

    Site Not Available

  • University of Iowa

    Iowa City, Iowa 52242
    United States

    Active - Recruiting

  • University of Iowa Hospital & Clinics

    Iowa City, Iowa 52242
    United States

    Active - Recruiting

  • University of Kansas Medical Center

    Westwood, Kansas 66205
    United States

    Active - Recruiting

  • University of Kentucky

    Lexington, Kentucky 40536
    United States

    Active - Recruiting

  • SCRI - Hematology Oncology Clinic

    Baton Rouge, Louisiana 70809
    United States

    Active - Recruiting

  • SCRI - Hematology Oncology Clinic - Baton Rouge

    Baton Rouge, Louisiana 70809
    United States

    Active - Recruiting

  • Main Health Cancer Center Biddeford

    Biddeford, Maine 04005
    United States

    Active - Recruiting

  • MaineHealth Cancer Care - Biddeford

    Biddeford, Maine 04005
    United States

    Active - Recruiting

  • Local Institution - 001-881-B

    Brandywine, Maryland 20613
    United States

    Site Not Available

  • Maryland Oncology Hematology - Columbia

    Columbia, Maryland 21044
    United States

    Active - Recruiting

  • Maryland Oncology Hematology-Columbia

    Columbia, Maryland 21044
    United States

    Active - Recruiting

  • Local Institution - 001-881-A

    Silver Spring, Maryland 20904
    United States

    Site Not Available

  • Dana Farber Cancer Institute

    Boston, Massachusetts 02215
    United States

    Active - Recruiting

  • Dana-Farber Cancer Institute

    Boston, Massachusetts 02215
    United States

    Active - Recruiting

  • Massachusetts General Hospital

    Boston, Massachusetts 02114
    United States

    Active - Recruiting

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan 48201
    United States

    Active - Recruiting

  • Henry Ford Health System

    Detroit, Michigan 48202
    United States

    Active - Recruiting

  • Henry Ford Medical Center

    Detroit, Michigan 48377
    United States

    Active - Recruiting

  • Local Institution - 001-842-A

    Farmington Hills, Michigan 48334
    United States

    Site Not Available

  • Local Institution - 001-838-F

    Coon Rapids, Minnesota 55433
    United States

    Site Not Available

  • Local Institution - 001-838-E

    Edina, Minnesota 55435
    United States

    Site Not Available

  • Local Institution - 001-875 - D

    Edina, Minnesota 55435
    United States

    Site Not Available

  • Local Institution - 001-838-D

    Maplewood, Minnesota 55109
    United States

    Site Not Available

  • Local Institution - 001-875 - A

    Maplewood, Minnesota 55109
    United States

    Site Not Available

  • Local Institution - 001-822-A

    Minneapolis, Minnesota 55455
    United States

    Site Not Available

  • Local Institution - 001-838-C

    Minneapolis, Minnesota 55404
    United States

    Site Not Available

  • Local Institution - 001-838-G

    Minneapolis, Minnesota 55415
    United States

    Site Not Available

  • Masonic Cancer Center

    Minneapolis, Minnesota 55455
    United States

    Active - Recruiting

  • Minnesota Oncology

    Minneapolis, Minnesota 55102
    United States

    Active - Recruiting

  • USOR - Minnesota Oncology - Minneapolis Clinic

    Minneapolis, Minnesota 55404
    United States

    Active - Recruiting

  • University of Minnesota

    Minneapolis, Minnesota 55454
    United States

    Active - Recruiting

  • Mayo Clinic - Rochester

    Rochester, Minnesota 55905
    United States

    Active - Recruiting

  • Mayo Clinic in Minnesota

    Rochester, Minnesota 55905
    United States

    Active - Recruiting

  • Local Institution - 001-838-B

    Saint Louis Park, Minnesota 55426-5000
    United States

    Site Not Available

  • Metro-Minnesota Community Oncology Research Consortium

    Saint Louis Park, Minnesota 55416
    United States

    Active - Recruiting

  • Metro-Minnesota Community Oncology Research Consortium (MMCORC)

    Saint Louis Park, Minnesota 55416
    United States

    Active - Recruiting

  • Local Institution - 001-838-A

    Saint Paul, Minnesota 55101
    United States

    Site Not Available

  • Local Institution - 001-875 - B

    Saint Paul, Minnesota 55102
    United States

    Site Not Available

  • Local Institution - 001-875 - C

    Woodbury, Minnesota 55125
    United States

    Site Not Available

  • Central Care Cancer Center - Bolivar

    Bolivar, Missouri 65613
    United States

    Active - Recruiting

  • Goldschmidt Cancer Center

    Jefferson City, Missouri 65109
    United States

    Active - Recruiting

  • Goldschmidt Cancer Center- Central Region Medical Center

    Jefferson City, Missouri 65109
    United States

    Active - Recruiting

  • Frontier Cancer Center

    Billings, Montana 59102
    United States

    Active - Recruiting

  • Sisters of Charity of Leavenworth Health St. Marys

    Billings, Montana 59102
    United States

    Active - Recruiting

  • Local Institution - 001-544A

    Omaha, Nebraska 68118
    United States

    Site Not Available

  • Local Institution - 001-544B

    Omaha, Nebraska 68105-1850
    United States

    Site Not Available

  • Methodist Estabrook Cancer Center

    Omaha, Nebraska 68114
    United States

    Active - Recruiting

  • Nebraska Cancer Specialists

    Omaha, Nebraska 68130
    United States

    Active - Recruiting

  • University of Nebraska Medical Center

    Omaha, Nebraska 68198
    United States

    Active - Recruiting

  • Local Institution - 001-860A

    Henderson, Nevada 89052
    United States

    Site Not Available

  • Local Institution - 001-860B

    Henderson, Nevada 89074
    United States

    Site Not Available

  • Local Institution - 001-860C

    Henderson, Nevada 89052
    United States

    Site Not Available

  • USOR - Comprehensive Cancer Centers of Nevada - Southeast Henderson

    Henderson, Nevada 89074
    United States

    Active - Recruiting

  • Comprehensive Cancer Centers of Nevada

    Las Vegas, Nevada 89169
    United States

    Site Not Available

  • Local Institution - 001-860D

    Las Vegas, Nevada 89144
    United States

    Site Not Available

  • Local Institution - 001-860E

    Las Vegas, Nevada 89128
    United States

    Site Not Available

  • Local Institution - 001-860F

    Las Vegas, Nevada 89148
    United States

    Site Not Available

  • New York Oncology Hematology - Albany Medical Center

    Albany, New York 12206
    United States

    Active - Recruiting

  • Roswell Park

    Buffalo, New York 14263
    United States

    Active - Recruiting

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York 14203
    United States

    Active - Recruiting

  • Local Institution - 001-832

    Lake Success, New York 11042
    United States

    Site Not Available

  • Local Institution - 001-583

    New York, New York 10032
    United States

    Site Not Available

  • Memorial Sloan Kettering Cancer Center

    New York, New York 10065
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Cancer Center - New York

    New York, New York 10065
    United States

    Active - Recruiting

  • Perlmutter Cancer Center

    New York, New York 10016
    United States

    Active - Recruiting

  • Perlmutter Cancer Center - 34th Street

    New York, New York 10016
    United States

    Active - Recruiting

  • University of North Carolina

    Chapel Hill, North Carolina 27514
    United States

    Active - Recruiting

  • University of North Carolina Hospitals

    Chapel Hill, North Carolina 27514
    United States

    Active - Recruiting

  • FirstHealth Outpatient Cancer Center

    Pinehurst, North Carolina 28374
    United States

    Active - Recruiting

  • The Christ Hospital

    Cincinnati, Ohio 45219
    United States

    Active - Recruiting

  • The Christ Hospital Cancer Center

    Cincinnati, Ohio 45219
    United States

    Active - Recruiting

  • University of Cincinnati Health Barrett Cancer Center

    Cincinnati, Ohio 45267
    United States

    Active - Recruiting

  • Cleveland Clinic

    Cleveland, Ohio 44195
    United States

    Active - Recruiting

  • Cleveland Clinic Lerner College of Medicine

    Cleveland, Ohio 44195
    United States

    Active - Recruiting

  • Local Institution - 001-833 - A

    Columbus, Ohio 43210
    United States

    Site Not Available

  • Local Institution - 001-833 - B

    Columbus, Ohio 43221
    United States

    Site Not Available

  • Local Institution - 001-833 - C

    Columbus, Ohio 43203
    United States

    Site Not Available

  • Local Institution - 001-833 - D

    Columbus, Ohio 43212
    United States

    Site Not Available

  • Local Institution - 001-833 - F

    Columbus, Ohio 43210
    United States

    Site Not Available

  • Local Institution - 001-833 - G

    Columbus, Ohio 43221
    United States

    Site Not Available

  • Local Institution - 001-833 - H

    Columbus, Ohio 43201
    United States

    Site Not Available

  • Local Institution - 001-833 - I

    Columbus, Ohio 43212
    United States

    Site Not Available

  • Local Institution - 001-833 - J

    Columbus, Ohio 43203
    United States

    Site Not Available

  • OSU Medical Center

    Columbus, Ohio 43210
    United States

    Active - Recruiting

  • SCRI - Mark H. Zangmeister Cancer Center

    Columbus, Ohio 43219
    United States

    Active - Recruiting

  • The Ohio State University College of Medicine

    Columbus, Ohio 43210
    United States

    Active - Recruiting

  • Local Institution - 001-833 - E

    Gahanna, Ohio 43230
    United States

    Site Not Available

  • Kettering Cancer Center

    Kettering, Ohio 45429
    United States

    Site Not Available

  • Kettering Health Cancer Center - Main Campus

    Kettering, Ohio 45429
    United States

    Active - Recruiting

  • Local Institution - 001-836-A

    Kettering, Ohio 45429
    United States

    Site Not Available

  • Cancer Centers of Southwest Oklahoma - Leah M. Fitch Cancer Center

    Lawton, Oklahoma 73505
    United States

    Active - Recruiting

  • Local Institution - 001-580

    Oklahoma City, Oklahoma 73142
    United States

    Site Not Available

  • Local Institution - 001-584

    Tulsa, Oklahoma 74146
    United States

    Completed

  • Oklahoma Cancer Specialist & Research Institute

    Tulsa, Oklahoma 74146
    United States

    Active - Recruiting

  • Oklahoma Cancer Specialists and Research Institute (OCSRI) - Tulsa

    Tulsa, Oklahoma 74146
    United States

    Site Not Available

  • Local Institution - 001-586-A

    Bend, Oregon 97701
    United States

    Site Not Available

  • St. Charles Health System

    Bend, Oregon 97701
    United States

    Active - Recruiting

  • Willamette Valley Cancer Institute and Research Center - Eugene

    Eugene, Oregon 97401
    United States

    Active - Recruiting

  • Lehigh Valley Heath

    Allentown, Pennsylvania 18103
    United States

    Active - Recruiting

  • Lehigh Valley Physician Group Hematology Oncology

    Allentown, Pennsylvania 18103
    United States

    Active - Recruiting

  • Local Institution - 001-837-A

    Bethlehem, Pennsylvania 18017
    United States

    Site Not Available

  • Penn State Cancer Institute

    Hershey, Pennsylvania 17033-0850
    United States

    Active - Recruiting

  • Penn State Health Milton S. Hershey Medical Center

    Hershey, Pennsylvania 17033
    United States

    Active - Recruiting

  • Alliance Cancer Specialists

    Media, Pennsylvania 19063
    United States

    Active - Recruiting

  • USOR - Alliance Cancer Specialists - Media (Cancer Center at Riddle Memorial Hospital)

    Media, Pennsylvania 19063
    United States

    Active - Recruiting

  • Charleston Oncology P.A.

    Charleston, South Carolina 29414
    United States

    Completed

  • Medical University of South Carolina

    Charleston, South Carolina 29425
    United States

    Active - Recruiting

  • USOR - Charleston Hematology Oncology Associates

    Charleston, South Carolina 29414
    United States

    Active - Recruiting

  • Local Institution - 001-801-G

    Gallatin, Tennessee 37066
    United States

    Site Not Available

  • Local Institution - 001-801-A

    Hendersonville, Tennessee 37075
    United States

    Site Not Available

  • Local Institution - 001-801-D

    Hermitage, Tennessee 37076
    United States

    Site Not Available

  • Local Institution - 001-801-F

    Murfreesboro, Tennessee 37129
    United States

    Site Not Available

  • Local Institution - 001-801-B

    Nashville, Tennessee 37203
    United States

    Site Not Available

  • Local Institution - 001-801-C

    Nashville, Tennessee 37211
    United States

    Site Not Available

  • Local Institution - 001-801-E

    Nashville, Tennessee 37207
    United States

    Site Not Available

  • Tennessee Oncology - Nashville - Centennial Clinic - Medical Oncology

    Nashville, Tennessee 37203
    United States

    Active - Recruiting

  • Tennessee Oncology/The Sarah Cannon Research Institute

    Nashville, Tennessee 37203
    United States

    Active - Recruiting

  • Local Institution - 001-888-B

    Arlington, Texas 76012
    United States

    Site Not Available

  • Texas Oncology-Arlington

    Arlington, Texas 76014
    United States

    Site Not Available

  • USOR - Texas Oncology Dallas Fort Worth West (DFWW) - Arlington South

    Arlington, Texas 76012
    United States

    Active - Recruiting

  • USOR - Texas Oncology - Austin Central

    Austin, Texas 78731
    United States

    Active - Recruiting

  • Local Institution - 001-848a

    Conroe, Texas 77384
    United States

    Site Not Available

  • Mary Crowley Cancer Research

    Dallas, Texas 75231
    United States

    Active - Recruiting

  • Mary Crowley Cancer Research - Medical City Hospital

    Dallas, Texas 75230
    United States

    Active - Recruiting

  • Texas Oncology at Presbyterian Dallas

    Dallas, Texas 75231
    United States

    Active - Recruiting

  • Texas Oncology- DFW

    Dallas, Texas 75246
    United States

    Active - Recruiting

  • USOR - Texas Oncology - Dallas Fort Worth (DFW) - Baylor Charles A. Sammons Cancer Center

    Dallas, Texas 75246
    United States

    Active - Recruiting

  • USOR - Texas Oncology - Dallas Fort Worth (DFW) - Presbyterian Cancer Center Dallas

    Dallas, Texas 75231
    United States

    Active - Recruiting

  • USOR Texas Oncology Baylor Charles A. Sammons Cancer Center

    Dallas, Texas 75246
    United States

    Active - Recruiting

  • USOR - Texas Oncology Northeast Texas - Denison

    Denison, Texas 75020
    United States

    Active - Recruiting

  • Texas Oncology

    Fort Worth, Texas 76104
    United States

    Site Not Available

  • Texas Oncology - Dallas Fort Worth (DFW) - Fort Worth

    Fort Worth, Texas 76104
    United States

    Active - Recruiting

  • Local Institution - 001-935A

    Houston, Texas 77090
    United States

    Site Not Available

  • Oncology Consultants - Texas Medical Center

    Houston, Texas 77030
    United States

    Active - Recruiting

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas 77030
    United States

    Active - Recruiting

  • University of Texas MD Anderson Cancer Center

    Houston, Texas 77030
    United States

    Active - Recruiting

  • Local Institution - 001-999

    Irving, Texas 75063
    United States

    Site Not Available

  • Local Institution - 001-935D

    Kingwood, Texas 77339
    United States

    Site Not Available

  • Lumi Research

    Kingwood, Texas 77339
    United States

    Active - Recruiting

  • Texas Oncology Midland

    Midland, Texas 79701
    United States

    Active - Recruiting

  • USOR - Texas Oncology - Midland Allison Cancer Center

    Midland, Texas 79701
    United States

    Active - Recruiting

  • START Center for Cancer Care

    San Antonio, Texas 78229
    United States

    Active - Recruiting

  • South Texas Accelerated Research Therapeutics

    San Antonio, Texas 78229
    United States

    Active - Recruiting

  • Local Institution - 001-935B

    Shenandoah, Texas 77380
    United States

    Site Not Available

  • Local Institution - 001-935C

    Spring, Texas 77389
    United States

    Site Not Available

  • Texas Oncology

    Sugar Land, Texas 77479
    United States

    Active - Recruiting

  • Texas Oncology - Sugar Land

    Sugar Land, Texas 77479
    United States

    Active - Recruiting

  • Local Institution - 001-935E

    Tomball, Texas 77375
    United States

    Site Not Available

  • Texas Oncology

    Tyler, Texas 75702
    United States

    Active - Recruiting

  • Texas Oncology - Northeast Texas Cancer and Research Institute - Tyler

    Tyler, Texas 75702
    United States

    Active - Recruiting

  • Texas Oncology - Waco

    Waco, Texas 76712
    United States

    Active - Recruiting

  • Texas Oncology Waco

    Waco, Texas 76712
    United States

    Active - Recruiting

  • Local Institution - 001-919

    Fairfax, Virginia 22031-4630
    United States

    Site Not Available

  • NEXT Virginia

    Fairfax, Virginia 22031
    United States

    Active - Recruiting

  • Virginia Cancer Specialists

    Fairfax, Virginia 22031
    United States

    Active - Recruiting

  • Hematology Oncology Associates of Fredericksburg

    Fredericksburg, Virginia 24408
    United States

    Active - Recruiting

  • USOR - Virginia Oncology Associates - Newport News

    Newport News, Virginia 23606
    United States

    Active - Recruiting

  • Virginia Oncology Associates-Newport News

    Newport News, Virginia 23606
    United States

    Active - Recruiting

  • Local Institution - 001-882-A

    Norfolk, Virginia 23502
    United States

    Site Not Available

  • Local Institution - 001-890-A

    Norfolk, Virginia 23502
    United States

    Site Not Available

  • Virginia Cancer Institute

    Richmond, Virginia 23230
    United States

    Active - Recruiting

  • Virginia Cancer Institute - West End

    Richmond, Virginia 23229
    United States

    Active - Recruiting

  • Fred Hutchinson Cancer Research Center

    Seattle, Washington 98109
    United States

    Active - Recruiting

  • Seattle Cancer Care Alliance

    Seattle, Washington 98109
    United States

    Active - Recruiting

  • USOR - Compass Oncology - Vancouver

    Vancouver, Washington 98684
    United States

    Active - Recruiting

  • USOR - Northwest Cancer Specialists, P.C. dba Compass Oncology - Vancouver Cancer Center

    Vancouver, Washington 98684
    United States

    Active - Recruiting

  • University Wisconsin Carbone Cancer Center

    Madison, Wisconsin 53792
    United States

    Active - Recruiting

  • University of Wisconsin Carbone Cancer Center

    Madison, Wisconsin 53792
    United States

    Active - Recruiting

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