Phase
Condition
Chest Pain
Cardiac Disease
Arrhythmia
Treatment
N/AClinical Study ID
Ages 19-75 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
paroxysmal, non-permanent, non-valvular AF. Patients with high burden of AF will beadmitted into the study ahead of low burden patients.
Low burden paroxysmal AF is defined as: ≥4 episodes of AF over the past 24months; episodes terminate spontaneously within 7 days or via cardioversionwithin 48 hours of onset.
High burden paroxysmal AF is defined as: ≥ 4 episodes of AF over the past 6months, with ≥ 2 episodes > 6 hours in duration; episodes terminate spontaneouslywithin 7 days or via cardioversion within 48 hours of onset.
Early persistent AF is defined as: ≥ 2 episodes of AF over the past 24 months;episodes are successfully terminated via cardioversion within 7 days of onset.
BMI equal to or greater than 27 kg/m^2, or central obesity using abdominalcircumference with ethnic specific values recommended by Canadian diabetesassociation.
one of hypertension or diabetes
Exclusion
Exclusion Criteria:
Permanent AF
Estimated survival < 2 years
Left ventricular ejection fraction < 40%
Weight > 300 lbs, treadmill cannot hold greater weights
Inability to walk one city block
Severe musculoskeletal or neurological problems making them unable to exercise safely
New York Heart Association class 3-4 heart failure
Severe aortic valve stenosis
Prior mitral valve surgery or severe stenosis or regurgitation
Hypertrophic cardiomyopathy
Patients with illnesses or medications that already cause atrial fibrillation on theirown, such as pericarditis, high doses of prednisone, and hyperthyroidism
Any other absolute and relative contraindications to exercise testing
Inability to speak and understand English
In atrial fibrillation at time of baseline testing
Defibrillator present
Study Design
Study Description
Connect with a study center
Garratt Wellness Centre
Richmond, British Columbia V7C 3S9
CanadaSite Not Available
Richmond Cardiology Clinic
Richmond, British Columbia V7C 5L9
CanadaActive - Recruiting
Richmond Health Services
Richmond, British Columbia V6Y 3T6
CanadaSite Not Available
Richmond Hospital Cardiac Rehabilitation
Richmond, British Columbia V6X 1A2
CanadaSite Not Available
Gordon and Leslie Diamond Health Care Centre
Vancouver, British Columbia V5Z 1M9
CanadaSite Not Available
Live Well Clinic
Vancouver, British Columbia V6M 3W6
CanadaSite Not Available
St. Paul's Healthy Heart Program
Vancouver, British Columbia V6Z 1Y6
CanadaSite Not Available
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