IPACK Block in Total Knee Arthroplasty

Last updated: October 21, 2019
Sponsor: Asklepieion Voulas General Hospital
Overall Status: Active - Recruiting

Phase

2

Condition

Knee Replacement

Treatment

N/A

Clinical Study ID

NCT03692858
8885/20-06-2018
  • Ages 14-80
  • All Genders

Study Summary

100 patients ASA I-III, undergoing total knee arthroplasty under spinal anesthesia, will be randomly assigned into one of two groups, namely group A (n=50), where an adductor canal block and an IPACK block will be performed preoperatively and group B (n=50) where an adductor canal block only will be performed preoperatively. All patients will receive a standardized multimodal approach, including pregabalin, paracetamol, and PCA with morphine. NRS scores in static and dynamic conditions during the first 48 hours postoperatively, morphine consumption during the first 24 hours postoperatively will be measured and additionally, patient satisfaction, complications, range of knee motion, moblization, functionality, delirium ocurence will be recorded. Chronic pain will be assessed in 3 and 6 months postoperatively.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Physical status according to American Society of Anesthesiologists (ASA) I-III

  • Patients scheduled for total knee arthroplasty

Exclusion

Exclusion Criteria:

  • Previous operation on same knee

  • Contraindication of spinal anesthesia, peripheral nerve blocks or any of the agentsused in the protocol

  • BMI above 32

  • Serious psychiatric, mental and cognitive disorders

  • Language barrier

  • Block failure

  • Chronic opioid, gabapentinoid use

  • Severe kidney disfunction

Study Design

Total Participants: 100
Study Start date:
October 01, 2018
Estimated Completion Date:
July 31, 2020

Connect with a study center

  • Asklepieion Hospital of Voula

    Athens, 16673
    Greece

    Active - Recruiting

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