Pain Outcomes Following Intralesional Corticosteroid Injections

Last updated: February 18, 2021
Sponsor: Vanderbilt University Medical Center
Overall Status: Completed

Phase

4

Condition

Hair Loss

Warts

Scleroderma

Treatment

N/A

Clinical Study ID

NCT03630198
181119
  • Ages > 12
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics. However, these injections can be quite painful, which leads many patients to discontinue treatment.

Often, the injection involves a mixture of local anesthetic and corticosteroids despite a lack of evidence that the use of lidocaine improves pain. Due to the acidic pH, the lidocaine component of the injection can actually cause a significant burning sensation during the procedure. Lidocaine does not have anti-inflammatory properties and does not treat the underlying pathology. By including another medication, lidocaine also adds cost and risk to the procedure.

The purpose of this study is to see if removing lidocaine from intralesional injections decreases the pain of injection.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • >12 years old presenting with an indication for intralesional steroid injection

Exclusion

Exclusion Criteria:

  • Unconsentable
  • Not a candidate for corticosteroid injection
  • Contraindication to lidocaine

Study Design

Total Participants: 31
Study Start date:
October 01, 2018
Estimated Completion Date:
September 01, 2019

Connect with a study center

  • Vanderbilt University Medical Center

    Nashville, Tennessee 37235
    United States

    Site Not Available

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