Post-exercise Hypotension After a Power Training Session in Older Adults With Hypertension

Last updated: January 12, 2021
Sponsor: Hospital de Clinicas de Porto Alegre
Overall Status: Completed

Phase

N/A

Condition

Stress

Williams Syndrome

Vascular Diseases

Treatment

N/A

Clinical Study ID

NCT03615625
85210618.1.0000.5327
  • Ages 60-75
  • All Genders

Study Summary

The main purpose of the present study was to evaluate the effect of a power training session on office and 24h ambulatory blood pressure in older adults with hypertension. As secondary outcomes, the investigators compared post-exercise hypotension, BP variability, and endothelial function between older men and women with hypertension.

The working hypothesis was that a single bout of power exercise would decrease both office and 24 h BP in comparison to a non-exercising control session and men and women would respond differently after a power training session.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Office blood pressure between 130-179 and 80-110 mmHg for systolic and diastolic bloodpressure, respectively;
  • Non-engaged in structured programs of exercise for the last 3 months since thebeginning of this study;
  • Able to perform the proposed exercises.

Exclusion

Exclusion Criteria:

  • Underlying cardiovascular disease previously diagnosticated by a doctor, occurred inthe last 24 months, such as: acute myocardial infarction, angina, stroke or heartfailure;
  • Diseases that reduce life expectancy;
  • Smokers and ex-smokers for less than six months;
  • BMI > 39.9 kg/m²
  • diabetic proliferative retinopathy.

Study Design

Total Participants: 24
Study Start date:
June 12, 2018
Estimated Completion Date:
January 01, 2020

Study Description

Participants randomly performed two experimental sessions: power exercise training (PT) and non-exercising control at seated rest (Con). They maintained their current antihypertensive medications throughout the trial. Each session was composed of 20 min of rest in the supine position, 40 min of PT or Con protocols, and 60 min of rest in supine position after protocols. The PT was composed of 3 sets of 8-10 repetitions of 5 exercises performed in the following order: leg press, bench press, knee extension, upright row, and knee flexion, using an intensity corresponding to 50 % of 1-RM and two-minute intervals between sets and exercises. The concentric phase of exercises during each repetition was performed "as fast as possible" while the eccentric phase lasted 1-2 seconds. During the Con, the participants remained seated rest on the same exercise machines, but without any exercise. Standardized office BP was performed before and during the first hour (in intervals of 15 min) after exercise and control sessions. Together with the office BP evaluation in the pre and post sessions, the endothelium-dependent brachial vascular function was evaluated using Flow-mediated dilation. Afterwards, participants underwent 24h ambulatory BP monitoring..

Connect with a study center

  • Hospital de Clinicas de Porto Alegre

    Porto Alegre, RS 90035-903
    Brazil

    Site Not Available

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