A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Inclusion Criteria:

• Must either be currently receiving treatment with, or have a history of havingfailed to respond to, or have a medical contraindication to at least 1 of thefollowing therapies: oral or intravenous corticosteroids, 6-mercaptopurine,methotrexate or azathioprine OR must either have or have had a history ofcorticosteroid dependency (that is an inability to successfully tapercorticosteroids without a return of the symptoms of ulcerative colitis [UC]) ORrequired more than 3 courses of corticosteroids in the past year

• Moderately to severely active UC (as defined by baseline Mayo score of 6 through 12 [endoscopy {sigmoidoscopy or colonoscopy} sub score assigned by local endoscopist],inclusive), including a (sigmoidoscopy or colonoscopy) sub score greater than orequal to (>=2)

• If receiving enteral nutrition, must have been on a stable regimen for at least 2weeks prior to the first administration of study intervention at Week 0.Participants who receive parenteral nutrition are not permitted to enroll in thetrial

• No history of latent or active tuberculosis prior to screening

• Must be up to date with all immunizations (that is, measles, mumps, rubella, andvaricella) in agreement with current local immunization guidelines forimmunosuppressed participants before Week 0

Exclusion Criteria:

• History of liver or renal insufficiency; significant cardiac, vascular, pulmonary,gastrointestinal, endocrine, neurologic, hematologic, rheumatologic, psychiatric (including suicidality), or metabolic disturbances

• History of malignancy or macrophage activation syndrome or hemophagocyticlymphohistiocytosis

• Have UC limited to the rectum only or to <20 percent (%) of the colon

• Presence of a stoma

• Presence or history of a fistula

• Contraindications to the use of golimumab or infliximab or anti-tumor necrosisfactor (TNF-alpha) therapy per local prescribing information