Pars Plana Vitrectomy Alone in the Treatment of Macular Schisis in High Myopic Eyes

Last updated: July 2, 2018
Sponsor: Aier School of Ophthalmology, Central South University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Retina

Eye Disease

Treatment

N/A

Clinical Study ID

NCT03586193
SHIRB2018014
  • All Genders

Study Summary

High myopic schisis (HMF) has the clinical feature of separation between retinal layers. It is sometimes accompanied with foveal retinal detachment, macular lamellar hole, epiretinal membrane and vitreous retraction. HMF may develop to macular hole, macular detachment and will damage the visual function. Pars plana vitrectomy (PPV) is a commonly used surgery in the treatment of HMF. PPV together with internal limiting membrane (ILM) peeling and long-term gas tamponade was reported to be safe and effective. But nowadays there was no available long-term gas in our country. Also, whether ILM peeling is necessary remains controversial, Indole cyanine green (ICG)was proved to have potential toxicity to the retina and the ILM peeling has the risk of causing secondary macular hole. We propose to make a prospective nonrandomized controlled study to evaluate the safety and efficiency of using PPV alone in the treatment of HMF.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Patients diagnosed as high myopic macular retinoschisis, with axial length more than 26.5mm.

  2. Morphologic manifestation in OCT shows split between retinal layers in macular area.

  3. Patients without severe systemic disease and can tolerate surgery.

Exclusion

Exclusion Criteria:

  1. Patients also have other ocular disease, including glaucoma, keratitis,uveitis,retinal detachment,etc.

  2. Patients with nystagmus or have difficult to open the eye.

  3. Patients with severe systemic disease and cannot tolerate surgery.

Study Design

Total Participants: 40
Study Start date:
May 01, 2018
Estimated Completion Date:
May 31, 2019

Connect with a study center

  • Shanghai Aier Eye hospital

    Shanghai, 200000
    China

    Active - Recruiting

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