Primary Failure of Eruption (PFE) : Highlighting of Clinical, Radiological and Genetic Diagnostic Criteria: Consequences on the Therapeutic Management

Last updated: August 16, 2024
Sponsor: University Hospital, Strasbourg, France
Overall Status: Active - Recruiting

Phase

N/A

Condition

Smallpox

Treatment

genetic analysis

CT scan of maxillary and mandible

teleradiography

Clinical Study ID

NCT03580785
6641
  • Ages > 6
  • All Genders

Study Summary

The primary purpose of the study is to identify clinical, radiological and genetic diagnostic criteria for Primary Failure of Eruption (PFE).

The secondary purposes are to highlight the genotype-phenotype correlations in the PTHR1 and non-PTHR1 forms and analyze the therapeutic failures.

Eligibility Criteria

Inclusion

Inclusion criteria:

  • people over 6 years old

  • people with Primary Failure Eruption

Exclusion

Exclusion criteria:

  • children under 6 years old

  • endocrine pathology that may interfere with dental eruption

  • rickets

  • chemotherapy / radiotherapy

  • bisphosphonate treatment

Study Design

Total Participants: 50
Treatment Group(s): 5
Primary Treatment: genetic analysis
Phase:
Study Start date:
October 22, 2018
Estimated Completion Date:
October 12, 2025

Connect with a study center

  • Clinique dentaire

    Strasbourg, 67000
    France

    Active - Recruiting

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