Prevalence of Abnormal Postures in Parkinson's Disease

Last updated: July 14, 2018
Sponsor: Universita di Verona
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT03573232
Università di Verona
  • Ages > 18
  • All Genders

Study Summary

Postural abnormalities represent disabling and painful complications in patients with Parkinson's disease (PD). The stooped posture is a typical feature of PD but with advancing of disease more severe body abnormalities can affect people with PD. These deformities include Pisa syndrome, camptocormia, antecollis, scoliosis and striatal deformities related to hand (striatal hand) and/or toes (striatal toes).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Participants will be considered enrolled after signing the consent form;

  2. Diagnosis of Parkinson's disease;

Exclusion

Exclusion Criteria:

  1. Concomitant neurologic diseases known to negatively affect posture;

  2. A history of major spinal surgery or muscle and/or skeletal diseases;

  3. Treatment with drugs potentially able to induce abnormal postures;

  4. Clinical features consistent with a diagnosis of atypical parkinsonism;

Study Design

Total Participants: 794
Study Start date:
March 07, 2018
Estimated Completion Date:
October 07, 2018

Study Description

Postural abnormalities represent disabling and painful complications in patients with Parkinson's disease (PD). The first postural trunk deviation in PD was first described by James Parkinson himself and recognized as stooped simian appearance, with flexion of the hips and knees, and rounding of the shoulders. Although the stooped posture is a typical feature, more severe spinal misalignment (and deformities) can affect people with PD. These postural deformities include Pisa syndrome (PS), camptocormia (CP), antecollis (AC), scoliosis (S) and striatal deformities related to hand (striatal hand) and/or toes (striatal toes). The prevalence of these postural deformities is variable because several diagnostic criteria have been used to characterize each deformity. Recently, a consensus of diagnostic criteria has been reached in literature permitting us to better mapping the presence of these deformities in people with PD.

Connect with a study center

  • Department of Experimental and Clinical Medicine - University "Politecnica delle Marche" Ancona -Italy. Neurorehabilitation Clinic - Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona.

    Ancona,
    Italy

    Active - Recruiting

  • Department of Neuroscience, Imaging and Clinical Sciences, University G.d'Annunzio of Chieti-Pescara

    Pescara,
    Italy

    Active - Recruiting

  • Neurology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

    Pisa,
    Italy

    Active - Recruiting

  • IRCCS San Raffaele CTC Centro Parkinson Via della Pisana 235, 00163 Roma

    Roma,
    Italy

    Active - Recruiting

  • Dipartimento di Neuroscienze A.O. Città della Salute e della Scienza di Torino

    Torino,
    Italy

    Active - Recruiting

  • Clinica Neurologica, Dipartimento di Scienze Neurologiche, Chirurgiche e della Salute, Azienda Ospedaliera Universitaria integrata, Universita' di Trieste

    Trieste,
    Italy

    Active - Recruiting

  • Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona

    Verona, 37134
    Italy

    Active - Recruiting

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