Last updated: August 3, 2021
Sponsor: American British Cowdray Medical Center
Overall Status: Active - Not Recruiting
Phase
3
Condition
Sepsis And Septicemia
Stress
Low Blood Pressure (Hypotension)
Treatment
N/AClinical Study ID
NCT03557229
ABC-18-19
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Diagnosis of septic shock in the last 24 hours characterized by refractory hypotensionand vasopressor requirement despite sufficient fluid resuscitation (20 mL/kg ofcolloids or 40 mL/kg of crystalloids) to maintain a blood pressure ≥ 65 mmHg with alactate> 2 mmol/L.
- Admitted to the ICU of the ABC Medical Center.
- Give informed consent.
Exclusion
Exclusion Criteria:
- Patients who refuse to be included.
- Chronic or recent use of steroids.
- Use of statins.
- Patients receiving some type of antioxidant treatment.
- Any contraindication to the use of vitamin C, vitamin E, n-acetylcysteine ormelatonin.
- Pregnant women.
Study Design
Total Participants: 131
Study Start date:
July 23, 2018
Estimated Completion Date:
June 30, 2022
Connect with a study center
Centro Médico ABC
Mexico City, 05300
MexicoSite Not Available
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