Food-effect, Drug-Drug Interaction (DDI), and Formulation Bridging Study

Inclusion Criteria:

• Male or female between 18 to 55 years old
• Male subjects must abstain from sexual intercourse or use a highly effective method ofbirth control
• Women of child bearing potential must have a negative pregnancy test and eitherabstain from sex or use a highly effective method of birth control
• Body Mass Index (BMI) 18 to 32 kg/m2
• Willing and able to give informed consent
• Additional inclusion criteria apply

Exclusion Criteria:

• Planning to conceive a child during the study or within 2 months after the last doseof study drug
• Is positive for hepatitis A, B or C, and/or HIV
• Has clinically significant abnormalities in baseline laboratory evaluations
• Subject has a clinically significant abnormal electrocardiogram (ECG)
• Participated in another clinical trial of an investigational drug (or medical device)within 30 days prior to screening or is currently participating in another trial of aninvestigational drug (or medical device)
• Additional exclusion criteria apply