Testicular Growth During Puberty in Boys With and Without a Left-sided Varicocele

Last updated: October 13, 2019
Sponsor: Universiteit Antwerpen
Overall Status: Active - Recruiting

Phase

N/A

Condition

Male Hormonal Deficiencies/abnormalities

Treatment

N/A

Clinical Study ID

NCT03540056
B300201730926
  • Ages 11-20
  • Male
  • Accepts Healthy Volunteers

Study Summary

Prospective observational study.

A varicocele is defined as a dilatation of the veins in the plexus pampiniformis in the testicles. Varicoceles are a diagnostic dilemma and a therapeutic challenge. Most of the boys with a varicocele don't show any symptoms, but approximately 15-20% experience some sort of infertility later during their life. There still isn't any consensus on when treating the patient is the right choice. Reliable scientific research about parameters able to predict the later stages of the boy with a varicocele is therefore needed. The purpose of this study is to how testicular growth could predict the outcome of boys with a varicocele.

During this study, testicular growth in boys with and without a left-sided varicocele will be examined in different schools using ultrasound to measure the testicular volumes, the PRF and the TAI to be able to collect sufficient data with the purpose to be able to predict whether testicular growth is a significant predictor on the progression of a varicocele.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Boys aged 11-16 years without any evidence of a current or past pathology influencingtesticular growth

Exclusion

Exclusion Criteria:

  1. Boys with a current or past inguinoscrotal pathology (varicocele, testicularmicrolithiasis, cryptorchidism, retractile testis, orchidectomy, testicular torsion,orchitis or epididymitis, hypospadias, inguinal hernia, oeprated varicocele, hydroceleand epididymal cysts)

  2. Boys with evidence of disorders influencing testicular growth (e.g. growth disorders)

  3. Boys with missing or incomplete data on Tanner stages for genital development

  4. Boys with a psychiatric disorder

Study Design

Total Participants: 600
Study Start date:
October 10, 2012
Estimated Completion Date:
September 30, 2022

Connect with a study center

  • Antwerp University Hospital

    Edegem, Antwerp 2650
    Belgium

    Active - Recruiting

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