Effect of Fertility-sparing Therapy of Early Endometrial Cancer

Last updated: May 24, 2018
Sponsor: Peking University People's Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Vaginal Cancer

Endometriosis

Endometrial Cancer

Treatment

N/A

Clinical Study ID

NCT03538704
2018ECFerSp
  • Ages 18-40
  • Female

Study Summary

The purpose of this study is to investigate the effect of Fertility-sparing Therapy of Early Endometrial Cancer.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • ages of no more than 40

  • with a strong desire of fertility preservation

  • International Federation of Gynecology and Obstetrics (FIGO) 2009 stage Ⅰa grade 1~2with lesion confined in endometrium

  • pathology expression of progestin receptors (PRs) and estrogen receptors

Exclusion

Exclusion Criteria:

  • not eligible for pregnancy or delivery

  • evidence of suspected extrauterine or distant metastasis

  • complicated with any other malignancy

  • severe medical complications

  • contraindication of oral progestin

  • uncontrolled epilepsy, central nervous system disease or mental disorder history inpatients which Influence clinical research compliance judging by the researcher.

Study Design

Total Participants: 80
Study Start date:
January 01, 2015
Estimated Completion Date:
December 31, 2020

Study Description

This is a prospective, multi center, open, randomized, controlled clinical trial. All endometrial cancer (EC) or atypical hyperplasia (AH) patients who met the fertility-sparing indications in the hospitals involved in this study were recruited. Then the investigators conducted assessment, treatment and follow up according to the standard procedure. General information, therapeutic regimen, side effects, oncological and pregnant results were collected for risk factors analysis.

Connect with a study center

  • Peking University People's Hospital

    Beijing, Beijing 100044
    China

    Active - Recruiting

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