Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery

Phase

2/3

Condition

Urinary Incontinence

Genitourinary Prolapse

Enuresis

Treatment

N/A

Clinical Study ID

NCT03524339

Tamsulosin for POUR

Ages > 18
Female
Accepts Healthy Volunteers

Study Summary

This is a placebo controlled randomized controlled trial of perioperative use of tamsulosin to prevent postoperative urinary retention in female pelvic reconstructive surgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Patients must be 18 years or older as well as willing and able to provide informedconsent
Patients must be undergoing a scheduled surgery for pelvic organ prolapse or urinaryincontinence
Standard postoperative plan must include admission to the hospital with foleycatheterization overnight the night after surgery, and planned removal of foleycatheter and active voiding trial on postoperative day 1.

Exclusion

Exclusion Criteria:

Patient unable or unwilling to provide informed consent
Severe allergy to sulfa drugs
Known allergy to tamsulosin or another alpha antagonist medication
History of urinary retention
Planned bladder catheterization greater than 24 hours after surgery
Current use of alpha antagonist medication for hypertension
End stage renal or liver disease

Study Design

August 01, 2018

June 09, 2020

Connect with a study center

University Hospitals
Cleveland, Ohio 44106
United States
Site Not Available
University Hospitals Cleveland Medical Center
Cleveland, Ohio 44106
United States
Site Not Available

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