Healing Osteoarthritic Joints in the Wrist With Adult ADRCs

Inclusion Criteria:

1. Males and females ages: 18 - 75.

2. Clinical symptoms consistent with wrist osteoarthritis.

3. Diagnosed with wrist osteoarthritis on radiographs.

4. The ability of subjects to give appropriate consent or have a legally authorizedrepresentative available.

Exclusion Criteria:

1. Subjects who have a documented history or presence of inflammatory arthritis,rheumatoid arthritis, severe osteoporosis, sepsis and chondrocalcinosis in the wrist

2. Subjects who have a documented diagnosis of carpal tunnel syndrome.

3. Insufficient amount of subcutaneous tissue to allow recovery of 100ml oflipoaspirate

4. History of systemic malignant or local neoplasms on affected limb within last 5years

5. Subject is receiving immunosuppressant therapy or has known immunosuppressive orsevere autoimmune disease that requires chronic immunosuppressive therapy (e.g.,human immunodeficiency virus, systemic lupus erythematosus, etc.)

6. Subjects who have received a corticosteroid injection in the treatment site

7. Subjects on an active regimen of chemotherapy

8. Allergy to sodium citrate of any "caine" type of local anesthetic

9. Subjects pregnant or breast feeding

10. Subject is in the opinion of the Investigator or designee, unable to comply with therequirements of the study protocol or is unsuitable for the study for any reason.This includes completion of patient reported outcome instruments

11. Subjects who have document allergy to radiographic guidance agents.

12. Subject is currently participating in another clinical trial that has not yetcompleted its primary endpoint

13. History of tobacco use within the last 3 months

14. Subjects with documented with a history of alcohol or drug abuse

15. Subjects who have a documented history of HIV, Hepatitis B, and Hepatitis C

16. Subject is part of a vulnerable population who, in the judgment of the investigator,is unable to give Informed Consent for reasons of incapacity, immaturity, adversepersonal circumstances or lack of autonomy. This may include: Individuals withmental disability, persons in nursing homes, children, impoverished persons, personsin emergency situations, homeless persons, nomads, refugees, and those incapable ofgiving informed consent. Vulnerable populations also may include members of a groupwith a hierarchical structure such as university students, subordinate hospital andlaboratory personnel, employees of the Sponsor, members of the armed forces, andpersons kept in detention.