Surgeon Infiltration QL Block Comparison

Last updated: February 6, 2024
Sponsor: Duke University
Overall Status: Completed

Phase

4

Condition

Pressure Ulcer

Treatment

QL Block

Liposomal Bupivicaine

Clinical Study ID

NCT03496610
Pro00087144
  • Ages 18-75
  • All Genders

Study Summary

The purpose of this study is to learn if using a Quadratus Lumborum (QL) plane injection technique (also called a "nerve block") that numbs the nerves going to the abdominal area improve pain control after surgery compared to administration of local anesthetic directly to the surgical incision. The QL block technique uses a numbing solution (local anesthetics) that is injected next to nerves located along muscles in the back to reduce pain. This block will not affect movement in the leg and/or make the legs weak. Some institutions, including Duke, use the QL block for patients having various abdominal surgeries, with the hope of providing good pain relief combined with improved mobility after surgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • English speaking
  • ASA 1-2 patients undergoing living donor nephrectomy

Exclusion

Exclusion Criteria:

  • ASA 3 or 5
  • Diagnosis of chronic pain
  • Daily chronic opioid use (over 3 months of continuous opioid use)
  • Inability to communicate pain scores or need for analgesia
  • Infection at the site of block placement
  • Pregnant women (as determined by standard of care day-of surgery urine bHCG)
  • Intolerance/allergy to local anesthetics
  • Weight <50 kg
  • Suspected or known addiction to or abuse of illicit drug(s), prescription medicine(s),or alcohol within the past 2 years
  • Uncontrolled anxiety, schizophrenia, or other psychiatric disorder that, in theopinion of the investigator, may interfere with study assessments or compliance
  • Current or historical evidence of any clinically significant disease or conditionthat, in the opinion of the investigator, may increase the risk of surgery orcomplicate the subject's postoperative course

Study Design

Total Participants: 44
Treatment Group(s): 2
Primary Treatment: QL Block
Phase: 4
Study Start date:
January 25, 2021
Estimated Completion Date:
February 23, 2023

Connect with a study center

  • Duke University

    Durham, North Carolina 27705
    United States

    Site Not Available

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