Recombinant Human Thrombopoietin(rhTPO) in Pregnancy With Immune Thrombocytopenia

Inclusion Criteria:

1. Meet the diagnostic criteria for immune thrombocytopenia.

2. 18-50 years of age; gestational age over 32 weeks;

3. No response to the treatment of glucocorticoids and / or intravenous immunoglobulin (astable dose of glucocorticoid could be accepted);

4. Platelet transfusion was not effective.

5. Platlet count of the patients <30* 10^9/L and had the risk of bleeding or bleeding.

6. No obvious abnormalities in liver and kidney function had (1.5 times higher thannormal limit of the serum urea nitrogen, creatinine, serum transaminase and bilirubin );

7. No severe cardiac and pulmonary dysfunction;

8. No history of mental illness;

9. Voluntarily signed written informed consent.

Exclusion Criteria:

1. A history of serious allergies to biologics;

2. The history of thrombosis;

3. Thromboembolic or hemorrhagic disease;

4. Patients who are deemed unsuitable for the study by the investigator.