Effects of Yangxinshi Pills on the Exercise Tolerance of the Patients With Coronary Heart Disease

Inclusion Criteria:

• Age 40 ~ 75, gender is not limited

• Have a clear history or ECG of hospital myocardial infarction , diagnosed as coronaryheart disease by imaging diagnosis

• Sign the informed consent voluntarily

Exclusion Criteria:

• History of hospitalization for acute coronary syndrome in past 3 months

• Uncontrolled grade 3 hypertension（≥180/100mmHg）or hypotension（＜90/60mmHg）

• History of stroke (cerebral hemorrhage, subarachnoid hemorrhage, cerebral thrombosis,cerebral embolism and stroke of unknown type) or lower extremity arterial disease inthe past 6 months

• In past 6 months, have medical history of: pregnancy, prepare or suspected ofpregnancy, abortion, breastfeeding or after childbirth

• Combined episode bronchial asthma or chronic obstructive pulmonary disease,bradycardia (resting heart rate <60bpm) or atrioventricular block

• Severely allergic constitution, known or likely to be allergic to the test drug or itscomponents

• Known bleeding tendency or hemorrhagic disease

• Patients with severe liver and kidney dysfunction (creatinine clearance ≤ 40ml / minor in the active stage of kidney disease, serum aminotransferase ≥ 2 × upper limit ofclinical reference), other life-threatening serious primary or psychiatric diseasesand malignant tumors

• Any other situations that researchers believe may affect the clinical research