The Incidence of Aphasia, Dysarthria and Dysphagia Following Stroke

Last updated: September 5, 2024
Sponsor: University Hospital, Ghent
Overall Status: Completed

Phase

N/A

Condition

Speech Disorders

Stroke

Cerebral Ischemia

Treatment

Screening and diagnosis of aphasia, dysarthria, dysphagia

Clinical Study ID

NCT03472625
B670201835160
  • All Genders

Study Summary

The objective of the study is to estimate the incidence and recovery of aphasia, dysarthria and dysphagia in an acute setting (first week) with the NIHSS sub-item scores for language and speech and a dysphagia screening.

Furthermore, we will evaluate the severity of aphasia, dysarthria and dysphagia in an acute setting (first few days) with standardized measurements (ScreeLing, BNT, NSVO-Z, perceptual assessment, MASA/FOIS).

To evaluate the effect of early IVT/EVT in patients with ischemic stroke on functional outcomes for language and speech via the NIHSS scale.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Acute stroke patients admitted at the Acute Stroke Unit at the university hospital (Ghent)

Exclusion

Exclusion Criteria:

  • Previous aphasia, dysarthria, dysphagia

Study Design

Total Participants: 557
Treatment Group(s): 1
Primary Treatment: Screening and diagnosis of aphasia, dysarthria, dysphagia
Phase:
Study Start date:
March 14, 2018
Estimated Completion Date:
October 04, 2019

Study Description

Study population:

Patients who are admitted to the acute Stroke Unit of the University Hospital Ghent will be recruited.

Study course:

The study has a prospective, observational design, with each participant receiving regular standard of care as follows: patients will undergo a clinical examination by a staff neurologists or the present attending in the emergency room. Tailored medical treatment will be given to each patient considering the type of stroke etc. as is standard of care (e.g. thrombolysis and/or thrombectomy for patients with ischemic stroke). Patients that are stable enough are transferred to the Stroke Unit where the neurologist or attending of the unit will reassess all stroke patients. NIHSS scores will be reported at least at day 2 +/- 1. A dysphagia screening is performed by the Stroke Unit nurses when the patient arrives at the Stroke Unit. The scores of the sub-items language and speech of the NIHSS and the dysphagia screening combined with a general screening by a speech language pathologist will be used to confirm or discard aphasia, dysphagia and dysarthria (incidence). When aphasia, dysarthria and/or dysphagia is confirmed, standardized tests will be performed. For this study, data of the following tests will be included for analysis: ScreeLing and/or BNT (aphasia), NSVO-Z and a perceptual assessment (dysarthria), MASA and/or the FOIS (dysphagia). At day 7 +/- 1, NIHSS scores will be reassessed (recovery in time). The diagnostic assessments and the NIHSS sub-items speech/language will be used to investigate the severity and recovery of the symptoms in time. Reports of the neurological clinical examination at follow-up will be retrospectively investigated if possible for additional information about recovery in time.

The total duration of data collection will be approximately 1 week and if possible three months follow-up.

Connect with a study center

  • University Hospital, department of neurology

    Ghent, East-Flanders 9000
    Belgium

    Site Not Available

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