Therapeutic Effects of Endoscopic Ablation of Hunner Lesions in Interstitial Cystitis/ Bladder Pain Syndrome Patients

Inclusion Criteria:

1. Male and female aged 18 yrs or greater

2. Patients diagnosed with BPS(Bladder Pain Syndrome)

3. Symptom persisted more than 6 months

4. Pain VAS ≥4

5. O'Leary-Sant Interstitial Cystitis questionnaire (IC-Q) scores 12 or greater withpain and nocturia domain scores > 2.

6. Pelvic Pain and Urgency/Frequency Patient Symptom Scale(PUF) >13

7. No history of cystoscopy within 2yrs.

Exclusion Criteria:

1. History of augmentation cystoplasty or previous transurethral coagulation/resectiondue to BPS

2. Child-bearing potential, pregnant or nursing women.

3. Mean voided volume lesser than 40ml or over than 400ml.

4. Hematuria exceeds 1+ in the urinary dipstick (dipstick) examination.

5. Urinary tract infection during run-in periods.

6. Genitourinary tuberculosis or bladder,urethral and prostate cancer

7. Recurrent urinary tract infection

8. History of hysterectomy,mid-urethral sling,pelvic organ prolapse repair,vaginaldelivery or Cesarean section,prostate operation or treatment etc within 6months.

9. Neurologic disease history of cerebral infarction,multiple sclerosis or parkinsonismetc.-