Honghe Fujie Lotion for the Treatment of Bacterial Vaginosis

Inclusion Criteria:

1. Premenopausal women with sex history.

2. Age: 20 - 50 years.

3. Clinical diagnosis of Bacterial Vaginosis.

4. Nugent scale ≥7.

5. Patient is willing to participate voluntarily and to sign a written patient informedconsent.

Exclusion Criteria:

1. Evidence of other female genital tractor infectious diseases (e.g. trichomonasvaginitis, VVC, suspected gonorrhea，HSV infection and pointed condyloma etc.).

2. Pruritus vulvae or pain caused by nonneoplastic epithelial disorders of vulva（e.g.Vulvar squamous epithelial hyperplasia ,vulvar lichen, diabetic vulvitis etc.).

3. Server gynecopathy（e.g. Gynecological malignant tumor etc.）.

4. Liver function impairment with the value of ALT or AST over 2-fold of normalvalue.Renal dysfunction with the value of serum creatinine over normal value.

5. Patient accompanied with server systemic diseases (gastrointestinal, cardio,cerebral,blood circulatory, endocrine, and renal system).

6. Receiving locally applied drugs within 1 week or currently using vaginal medicines.

7. Significant drug or alcohol abuse or a history of mental illness patients.

8. Researchers determine poor adherence, or any other unsuitable reasons for patients toparticipate in this study.

9. Diagnosis with other disease that necessities immunosuppressant or hormone therapy.

10. Pregnancy, breast feeding and the possible pregnancy during study. Patient who isparticipating in other trials or has been participated in other trials in recent 1months.

11. Allergic to one or more components of study medicine.