Last updated: October 4, 2024
Sponsor: University of Alabama at Birmingham
Overall Status: Active - Recruiting
Phase
N/A
Condition
Retina
Diabetic Retinopathy
Treatment
Generation of inducible pluripotent stem cells
Clinical Study ID
NCT03403699
300000173
Ages 21-98 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Any man or woman between the ages of 21- 98 years of age will be eligible toparticipate. To participate in the study as a study subject we will require: a) thesubject must either carry the diagnosis of diabetes or be a healthy aged control andb) the patient be willing and have the ability to cooperate with the eye exam andskin punch biopsy protocol.
Exclusion
Exclusion Criteria:
- We will apply the following exclusion criteria: a) evidence of ongoing acute orchronic infection (HIV, Hepatitis B or C, tuberculosis); b) ongoing malignancy; c)cerebral vascular accident or cerebral vascular procedure; d) current pregnancy; e)history of organ transplantation; f) presence of a graft (to avoid any effect of thegraft on inflammatory parameters; and g) patients with anemia. Subjects with AMD,glaucoma, uveitis, known hereditary degenerations or other significant ocularcomplications other than diabetic retinopathy will be excluded.
Study Design
Total Participants: 20
Treatment Group(s): 1
Primary Treatment: Generation of inducible pluripotent stem cells
Phase:
Study Start date:
January 11, 2018
Estimated Completion Date:
January 31, 2026
Study Description
Connect with a study center
University of Alabama at Birmingham
Birmingham, Alabama 35294
United StatesActive - Recruiting
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