Observational, Non-interventional Use of LIPUS to Mitigate Fracture Non-union in Patients at Risk

Inclusion Criteria:

1. Must be willing to provide voluntary informed consent

2. Male or female age 21-80 on fracture date

3. Must be willing to sign for release of medical insurance claim billing records fromthe treating clinician, pertaining to the fracture and fracture treatment

4. Fluency in English and/or Spanish

5. Prescriptive initiation of therapy with the EXOGEN Ultrasound Bone Healing System (Model number 71034400) for a specified fracture

6. Bone specific fracture

Exclusion Criteria:

1. Patient report of treatment with an electrical bone growth stimulation device (e.g.,pulsed electromagnetic field (PEMF) or capacitive coupling (CC) based devices) forbone fracture in 9-months pre-index period up to baseline phone contact

2. Pregnant on fracture index date

3. Evidence that prescription for EXOGEN has been written to treat a fracture non-unionor mal-union (i.e, ICD-10-CM code with seventh character modifier of K, P or S).

4. Evidence that prescription for EXOGEN has been written to treat a pathologicfracture (ICD-10-CM code M80. or M84.) or neuropathic bone (ICD-10-CM code M14.6)

5. Patient with a concurrent fracture of the other bones of interest

6. Patients who are or anticipate living or receiving fracture treatment outside of theUS during the post-index fracture period

7. Patient report of history of primary or metastatic bone cancer

8. Patient report of bone infection or osteomyelitis of index fracture at baselinecontact

9. Patient report of prior bone specific fracture in 9-months pre-index period

10. Patient prescribed EXOGEN as part of a Worker Compensation claim