Phase
Condition
Appendicitis
Treatment
N/AClinical Study ID
Ages 18-65 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
18 and 65 years old
A diagnosis of suppurative or gangrenous appendicitis based on:
metastatic right lower abdominal pain
lower abdominal tenderness and/or rebound tenderness
pyrexia (axillary temperature ≥ 37.5 °C), a WBC > 10*109/L on routine bloodexamination
Voluntary signing of written informed consent
Exclusion
Exclusion Criteria:
patients with an allergy to nitroimidazole
patients with a history of antibiotic therapy within the last 48 hours
patients with any condition likely to require broad spectrum antibiotics
patients who can not evaluate the efficacy or difficult to complete the desired courseof treatment
ALT and / or AST ≥ 1.5 times the ULN, and / or serum creatinine ≥ the ULN
patients with severe systemic diseases likely to affect therapy (e.g., cardiovascularabnormalities, unstable angina, high blood pressure, severe neuropathy, or epilepsy)
patients with other diseases or use other drugs which may interfere with the efficacyor safety of the drug
patients who participated other clinical trials within 6 months before the start ofthe trial
Pregnant women, breastfeeding women, women of childbearing age without effectivecontraceptive
Study Design
Study Description
Connect with a study center
PLA General Hospital
Beijing, 100853
ChinaActive - Recruiting
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