Periprosthetic Fracture Registry (PPFx)

Last updated: February 13, 2025
Sponsor: AO Innovation Translation Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT03378557
PPFx
  • Ages > 18
  • All Genders

Study Summary

This registry supports international data collection and research on PPFx treatments after hip and knee arthroplasty.

A registry such as this ultimately aims to provide far-reaching benefits to society including reduced morbidity and mortality, improved patient safety, improved quality of care and medical decision-making, reduced medical spending, and advances in orthopaedic science.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age ≥18 years

  • Post-operative PPFx after total or hemi hip or total or unicondylar kneearthroplasty (including the acetabulum, femur, patella and proximal tibia)requiring

  • osteosynthesis alone or

  • component revision plus plate/nail osteosynthesis

  • Informed consent obtained, i.e.:

  • Ability of the patient or assigned representative to understand thecontent of the patient information / Informed Consent Form

  • Signed and dated EC / IRB approved written informed consent

  • Ability to attend post-operative follow up visits

Exclusion

Exclusion Criteria:

  • Pregnancy or women planning to conceive within the study period

  • Prisoner

Study Design

Total Participants: 600
Study Start date:
December 31, 2018
Estimated Completion Date:
March 31, 2027

Study Description

To close the gap of missing clinical evidence regarding the treatment of periprosthetic fractures after arthroplasty of the hip or the knee with osteosynthesis.

To drive further study hypotheses and to answer unforeseen questions.

Main questions to be answered by the registry include (but are not exclusive) the following:

  1. Influence of implants on outcome

  2. Influence of surgical techniques on outcome

  3. Influence of bone grafting on outcome

  4. Identification of risk factors for failure

  5. Identification of postoperative rehabilitation programs and its possible influence on the outcome

  6. Influence of fracture type on outcome

  7. To serve as a comparative dataset for future studies with improved implants and techniques

Connect with a study center

  • Universitaire Ziekenhuiven Leuven

    Leuven,
    Belgium

    Active - Recruiting

  • Hospital Santa Clara

    Bogotá,
    Colombia

    Active - Recruiting

  • Charité Universitätsmedizin Berlin

    Berlin,
    Germany

    Active - Recruiting

  • BG-Unfallklinik Ludwigshafen

    Ludwigshafen,
    Germany

    Active - Recruiting

  • Universitätsklinikum Münster

    Münster,
    Germany

    Active - Recruiting

  • Hospital Universitario Son Llàtzer

    Palma De Mallorca,
    Spain

    Active - Recruiting

  • Universitätsspital Basel

    Basel,
    Switzerland

    Active - Recruiting

  • Kantonspital Baselland

    Liestal, 4410
    Switzerland

    Terminated

  • Universitätsspital Zürich

    Zürich,
    Switzerland

    Active - Recruiting

  • University of Missouri Health Care

    Columbia, Missouri 65201
    United States

    Active - Recruiting

  • Jersey City Medical Center RWJ Barnabas Health

    Jersey City, New Jersey 07302
    United States

    Active - Recruiting

  • Saint Barnabas Medical Center Livingston

    Livingston, New Jersey 07039
    United States

    Active - Recruiting

  • Vanderbilt University Medical Center

    Nashville, Tennessee 37232
    United States

    Active - Recruiting

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