Outcomes of Adipose Derived Mesenchymal Stem Cells on Sexual Hormone Deficiency

Inclusion Criteria:

• Age: 35 years to 70 years (Male) and from 35 years to menopause age (Female)

• Male: decrease in libido, decrease in intercourse frequency, erectile dysfunction,Difficulty in concentration, testosterone level ≤ 12 nMol/dL

• Female: reduced or absent menstruation after radiation exposure or chemotherapy; Hotflushes, excessive sweating, and anxiety, together with other symptoms associatedwith the menopause, AMH level ≤ 2 ng/ml and/or FSH level ≥ 10 mIU/ml.

• Patients signed the informed consent form

Exclusion Criteria:

• Surgery removal of endocrine glands

• Abnormalities in the endrocrine glands

• Hormone deficiency due to diabetes and other metabolic disorders

• Active autoimmune diseases

• Current usage of immunosuppressive drugs

• Coagulation disorders

• Allergy to anesthetic agents

• Severe health conditions such as cancer, failure of heart, lung, liver or kidney

• Active infections