Hunter Outcome Survey (HOS)

Inclusion Criteria:

1. Diagnosis of Hunter syndrome (biochemically and/or genetically)

2. Signed and dated written informed consent, as per either a or b below:

3. Prospective Participants: Signed and dated written informed consent from theparticipant or, for participants aged less than (<) 18 years (<16 years inScotland), parent and/or participant's legally authorized representative (LAR),and assent of the minor where applicable.informed consent must be obtained from LARs for cognitively impairedparticipants, where applicable.OR

4. Historical Participants: Signed and dated informed consent from theparticipant's LAR (where allowed by relevant individual country or siteregulations/laws). .

Exclusion Criteria:

1. Participants enrolled in an interventional clinical trial are not eligible.Participants may re-enroll once they have completed or withdrawn from the otherclinical study.

2. Participants receiving treatment for Hunter syndrome with an ERT product other thanElaprase are not eligible. Participants may enroll or re-enroll once they havestopped treatment with another ERT.